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新生儿和婴儿的轮状病毒感染——流行病学方面(作者译)

[Rota virus infection in the newborn and infant -- epidemiological aspects (author's transl)].

作者信息

Forster J, Luthardt T

出版信息

Klin Padiatr. 1979 Sep;191(5):472-6.

PMID:229307
Abstract

In a total of 406 sera an age-dependent pattern of complement fixing antibodies against Rotavirus (Nebraska calf diarrhea virus) was found: 85% of the adults had antibodies, infants in the second half-year of life had the lowest percentage (42%). Thereupon a Rotavirus survey was carried out in a newborn ward by means of electron microscopy, enzyme-linked immunosorbent assay and complement fixation test during three weeks in January/February 1978. A chronically high infection rate was discovered. Children acquired intestinal infection despite of complement fixing serum antibodies and very few showed a rise in antibody titer.

摘要

在总共406份血清中,发现了针对轮状病毒(内布拉斯加小牛腹泻病毒)的补体结合抗体的年龄依赖性模式:85%的成年人有抗体,生命后半期的婴儿抗体百分比最低(42%)。随后,于1978年1月/2月的三周内,在新生儿病房通过电子显微镜、酶联免疫吸附测定和补体结合试验进行了轮状病毒调查。发现感染率长期居高不下。尽管有补体结合血清抗体,儿童仍会感染肠道,而且很少有抗体滴度升高的情况。

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