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肯尼亚某农村地区影响母婴健康的因素。十一、肯尼亚马查科斯地区儿童血清中抗轮状病毒抗体

Agents affecting health of mother and child in a rural area of Kenya. XI. Antibodies against rotavirus in sera from children living in the Machakos District of Kenya.

作者信息

Metselaar D, Sack D A, Kapikian A Z, Muller A S

出版信息

Trop Geogr Med. 1978 Dec;30(4):531-5.

PMID:219569
Abstract

207 sera from children under 5 years of age and living in the Machakos District in Kenya were tested in the Complement Fixation Test for antibodies against rotavirus. Two different antigens were used. The superiority of 'O' antigen over Nebraska calf diarrhoea virus antigen was confirmed. After a fall to 29 percent in the 6-8 months age group, the percentage of children with antibodies quickly rises with age to 80 percent at the age of 24 months and to practically 100 percent at the age of 30 months. This age-immunity curve suggests that the majority of children contract infections with rotavirus between 6 and 23 months of age. This is conform the pattern usually found in temperate climate countries.

摘要

对来自肯尼亚马查科斯地区5岁以下儿童的207份血清进行了补体结合试验,以检测抗轮状病毒抗体。使用了两种不同的抗原。证实了“O”抗原比内布拉斯加小牛腹泻病毒抗原更具优势。在6 - 8个月龄组抗体阳性儿童比例降至29%后,抗体阳性儿童的比例随年龄迅速上升,24个月龄时达到80%,30个月龄时几乎达到100%。这种年龄-免疫曲线表明,大多数儿童在6至23个月龄之间感染轮状病毒。这与温带气候国家通常发现的模式相符。

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