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[缺血性心脏病患者在身体和信息负荷条件下心肌梗死发生的病理生理机制的比较分析]

[Comparative analysis of pathophysiologic mechanisms of myocardial infarction development under conditions of physical and information load in patients with ischemic heart disease].

作者信息

Sudzhaeva S G

出版信息

Patol Fiziol Eksp Ter. 1990 Sep-Oct(5):13-5.

PMID:2293150
Abstract

The results of examination on a bicycle ergometer and the information test with continuous electrocardiographic and hemodynamic control by means of impedance plethysmography showed that the cardiovascular system of patients with ischemic heart disease is desadapted to physical and informative load, which was manifested by ischemia of the myocardium and disorders of its contractility in both types of loading. The pathogenetic mechanisms of the development of myocardial ischemia in most patients with ischemic heart disease under conditions of physical and information loads differ. In information load, ischemia of the myocardium is a consequence of coronary vasospasm in 72.7% of patients and only in 27.3% of cases it is caused by deficient perfusion of the myocardium with blood in stenosed coronary arteries and increased myocardial requirements for oxygen. Inverse tendencies are encountered in physical load.

摘要

通过自行车测力计进行的检查结果以及借助阻抗体积描记法进行连续心电图和血流动力学控制的信息测试表明,缺血性心脏病患者的心血管系统对身体和信息负荷适应不良,这在两种负荷类型中均表现为心肌缺血及其收缩性紊乱。大多数缺血性心脏病患者在身体和信息负荷条件下发生心肌缺血的发病机制不同。在信息负荷情况下,72.7%的患者心肌缺血是冠状动脉痉挛的结果,仅27.3%的病例是由狭窄冠状动脉中血液对心肌灌注不足以及心肌对氧气需求增加所致。在身体负荷时则出现相反的趋势。

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