Dzizinskiĭ A A, Cherniak B A
Ter Arkh. 1984;56(12):28-32.
The authors provide the results of a comparative study of exercise tolerance (bicycle ergometry test) in 64 patients with coronary heart disease (CHD) and in 68 patients with associated CHD and cerebral atherosclerosis. During the latter syndrome the working capacity was lowered as a result of less economical work of the circulatory apparatus. In particular, physical loading in such patients was accompanied by marked increment of the heart rate and blood pressure elevation. Increased heart oxygen requirement in the second group patients during exercise was accompanied by more frequent ischemic alterations in the myocardium attended by ST segment depression on the ECG. It is concluded that concomitant cerebral atherosclerosis aggravates the basic pathogenetic mechanisms of CHD, namely the disagreement between myocardium oxygen requirement and supply.
作者提供了一项对比研究的结果，该研究针对64例冠心病（CHD）患者以及68例合并冠心病和脑动脉粥样硬化的患者进行了运动耐力（自行车测力计测试）研究。在后一种综合征中，由于循环系统工作效率降低，工作能力下降。特别是，这类患者进行体力负荷时会伴有心率显著增加和血压升高。第二组患者运动期间心脏需氧量增加，同时心肌缺血性改变更为频繁，心电图显示ST段压低。研究得出结论，合并脑动脉粥样硬化会加重冠心病的基本发病机制，即心肌需氧量与供氧量之间的失衡。
