Key Laboratory of Pharmaceutical Quality Control of Hebei Province & College of Pharmacy, Hebei University, Baoding, China.
Analyst. 2012 Oct 21;137(20):4860-6. doi: 10.1039/c2an36046b.
A rapid ultrasound-assisted surfactant-enhanced emulsification microextraction (UASEME) method coupled with gas chromatography-flame ionization detection (GC-FID) is proposed for the rapid screening of five phthalate esters in bottled beverages. In the UASEME procedure, a nonionic surfactant (Triton X-100) was used as the emulsifier, without application of any organic dispersive solvents typically required in dispersive liquid-liquid microextraction. Triton X-100 as the emulsifier accelerated the formation of fine droplets from the extraction solvent in the sample solution under ultrasound radiation, thus combining the advantages of dispersive liquid-liquid microextraction (DLLME) and ultrasound-assisted emulsification microextraction (UAEME). Under the optimum conditions, the enrichment factors of the five analytes ranged from 230 to 288 fold and the recoveries ranged from 89.3% to 100.1%. The limits of detection (LODs) based on signal to noise of 3 were 0.41-0.79 μg L(-1). Intra-assay and inter-assay precision, expressed as the relative standard deviation (RSD), were ≤5.46% and 5.81%, respectively. The proposed UASEME-GC/FID method was demonstrated to be simple, practical and environmentally friendly for the determination of trace phthalate esters in beverage samples.
提出了一种快速超声辅助表面活性剂增强乳化微萃取（UASEME）方法，并结合气相色谱-火焰离子化检测（GC-FID），用于快速筛选瓶装饮料中的五种邻苯二甲酸酯。在 UASEME 过程中，使用非离子表面活性剂（Triton X-100）作为乳化剂，无需使用通常在分散液 - 液微萃取中所需的任何有机分散溶剂。Triton X-100 作为乳化剂在超声辐射下加速从萃取溶剂中形成细小液滴，从而结合了分散液 - 液微萃取（DLLME）和超声辅助乳化微萃取（UAEME）的优点。在最佳条件下，五种分析物的富集因子范围为 230 至 288 倍，回收率范围为 89.3%至 100.1%。基于信噪比为 3 的检测限（LOD）为 0.41-0.79 μg L(-1)。日内和日间精密度，以相对标准偏差（RSD）表示，分别为≤5.46%和 5.81%。该方法简单、实用且环保，可用于测定饮料样品中的痕量邻苯二甲酸酯。
