Niu Ying-Mei, Hao Feng-Tong, Xia Yu-Jing
Department of Occupational Disease and Toxicology, Beijing Chaoyang Hospital, Capital University of Medical Sciences, Beijing, China
Department of Occupational Disease and Toxicology, Beijing Chaoyang Hospital, Capital University of Medical Sciences, Beijing, China.
Toxicol Ind Health. 2014 Jun;30(5):475-9. doi: 10.1177/0748233712457453. Epub 2012 Aug 29.
Sodium 3,5,6-trichloropyridin-2-ol (STCP) is an important intermediate for synthesizing organophosphate insecticide chlorpyrifos. At present, chlorpyrifos is one of the world's largest species of pesticide products. Many studies have focused on the toxicity of chlorpyrifos, but few reports have looked at the toxicity mechanism of STCP. Even fewer studies have looked at STCP poisoning. With increasing production and usage of STCP, the chances of such poisoning will increase. In this study, we present a report on four workers who helped in the industrial manufacture of STCP and who were affected by exposure to it. We hope that these case studies will provide a foundation for further research into STCP.
3,5,6-三氯吡啶-2-醇钠（STCP）是合成有机磷杀虫剂毒死蜱的重要中间体。目前，毒死蜱是全球最大的农药产品品种之一。许多研究聚焦于毒死蜱的毒性，但关于STCP毒性机制的报道较少。研究STCP中毒的更是少之又少。随着STCP生产和使用的增加，此类中毒的可能性也会上升。在本研究中，我们报告了4名参与STCP工业生产并因接触STCP而受到影响的工人。我们希望这些案例研究能为进一步研究STCP提供基础。
