Liu X A, Jiang M C, Huang P B, Zou T
Institute of Acupuncture and Moxibustion, China Academy of Traditional Chinese Medicine, Beijing.
Sheng Li Xue Bao. 1990 Dec;42(6):523-33.
The purpose of the present work is to study whether the analgesia of "Zusanli" EA was mainly produced by its noxious effect. The antidromic C waves on N. peroneus communis innervating the area of "Zusanli" point were recorded. When "Zusanli" point was stimulated by trains of stimuli, the amplitude of the antidromic C wave was obviously decreased due to collision with the orthodromic stimulation. It was suggested that EA of "Zusanli" could excite some C fibers. It was observed that when the stimulation intensity reached the threshold of C fiber, the NRM neurons were obviously activated, and when it reached or exceeded the intensity for producing the maximal C wave, the NRM neurons were highly activated. Therefore, EA analgesia is probably produced mainly by its noxious stimulus component, especially carried by C fibers, via a negative feedback mechanism in modulating pain.
本研究的目的是探讨“足三里”穴位电针镇痛是否主要由其有害效应产生。记录支配“足三里”穴区的腓总神经的逆向C波。当以串刺激刺激“足三里”穴时，由于与顺向刺激碰撞，逆向C波的幅度明显降低。提示“足三里”电针可兴奋某些C类纤维。观察到当刺激强度达到C类纤维阈值时，中缝大核（NRM）神经元明显激活，当达到或超过产生最大C波的强度时，NRM神经元高度激活。因此，电针镇痛可能主要由其有害刺激成分，尤其是由C类纤维传导的成分，通过负反馈机制调节疼痛而产生。
