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[大鼠脊髓中刺激背外侧索诱发的场电位]

[Field potentials evoked by stimulation of DLF in the rat spinal cord].

作者信息

Yin Y, Cheng Z F

机构信息

Department of Physiology, Xi'an Medical University.

出版信息

Sheng Li Xue Bao. 1990 Dec;42(6):534-9.

PMID:2293365
Abstract

When stimulation of DLF at cervical cord, a train of evoked potentials are recorded with a microelectrode at lumber level in rat. The longer slow positive potential wave, latency 7.22 +/- 1.41 ms, peak time 15 +/ 12 +/- 5.58 ms, duration 93 +/ 92 +/- 9.06 ms, is called DLF-FP. The negative center of the isopotential map of DLF-FP is located at 1.0-1.3 mm below the dorsal surface nearly in coincidence with that of the P1-FP evoked by the sural nerve stimulation. The amplitude of DLF-FP was decreased by picrotoxin and increased by strychnine. Both summation and inhibition can be observed between the potentials evoked by stimulation of the sural nerve and DLF. The results mentioned above show that DLF-FP is the reflection of primary afferent depolarization probably by the same spinal circuit underlying P1-FP.

摘要

当在大鼠颈髓刺激背外侧索(DLF)时,可在腰髓水平用微电极记录到一串诱发电位。其中较长的慢正电位波,潜伏期为7.22±1.41毫秒,峰值时间为15±12±5.58毫秒,持续时间为93±92±9.06毫秒,称为DLF-FP。DLF-FP等电位图的负中心位于背表面下方1.0 - 1.3毫米处,几乎与腓肠神经刺激诱发的P1-FP的负中心重合。DLF-FP的振幅被印防己毒素降低,被士的宁增加。在腓肠神经刺激诱发的电位与DLF诱发的电位之间可观察到总和与抑制现象。上述结果表明,DLF-FP可能是由与P1-FP相同的脊髓回路引起的初级传入去极化的反映。

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