从感染犬血液中分离的犬种布鲁氏菌 HSK A52141 菌株的全基因组序列。
Complete genome sequence of Brucella canis strain HSK A52141, isolated from the blood of an infected dog.
机构信息
Macrogen Inc., Gasan-dong, Geumcheon-gu, Seoul, Republic of Korea.
出版信息
J Bacteriol. 2012 Sep;194(18):5134. doi: 10.1128/JB.01125-12.
Abstract
Brucella canis infection can be clinically inapparent in dogs, and when infection goes unnoticed, there is a chance for dog-to-human transmission. A new strain of B. canis was isolated from the blood of an infected dog in order to analyze the pathogenic mechanism, compare genetic properties, and develop new genetic tools for early diagnosis of canine brucellosis. Herein, we report the complete genome sequence of the strain B. canis HSK A52141. This is the second complete genome sequence and biological annotation available for a member of B. canis.
摘要
犬布鲁氏菌感染在犬中可能临床无症状，当感染未被发现时，就有机会在犬与人之间传播。为了分析致病机制、比较遗传特性并开发用于犬布鲁氏菌病早期诊断的新遗传工具，从感染犬的血液中分离出一株新的犬布鲁氏菌菌株。在此，我们报告了该菌株 B. canis HSK A52141 的完整基因组序列。这是可获得的第二个犬布鲁氏菌成员的完整基因组序列和生物注释。
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