Bende Mats, Millqvist Eva
Department of Otorhinolaryngology, Central Hospital Skövde, Sweden.
Front Physiol. 2012 Jul 4;3:251. doi: 10.3389/fphys.2012.00251. eCollection 2012.
The aim of this study was to determine the prevalence of chronic cough in relation to upper airway symptoms, in a cross-sectional, population-based epidemiological study. Another aim was to relate coughing to other explanatory variables and risk factors. A random sample of 1900 inhabitants from the age of 20, stratified for age and gender, was recruited. Subjects were invited for clinical examinations that included questions about general odor intolerance, respiratory symptoms, and smoking habits, and a smell identification test. In total, 1387 volunteers (73% of the sample) were investigated. The overall prevalence of self-reported chronic cough was 6.3% [95% confidence interval (CI): 5.0-7.6%]. Female gender, age, height, BMI, and smoking were significantly related to cough. Furthermore, nasal blockage, nasal secretion, sneezing, asthma, odor and cold air sensitivity, and aspirin intolerance also related to cough with statistical significance, indicating a close connection between chronic cough and upper airway symptoms. In keeping with other studies, this study demonstrates that chronic cough is a widespread problem in society, and is about twice as common in women than in men.
在一项基于人群的横断面流行病学研究中,本研究的目的是确定与上呼吸道症状相关的慢性咳嗽患病率。另一个目的是将咳嗽与其他解释变量和风险因素联系起来。招募了1900名20岁及以上的居民作为随机样本,按年龄和性别分层。邀请受试者进行临床检查,包括询问一般气味不耐受、呼吸道症状和吸烟习惯,以及嗅觉识别测试。总共对1387名志愿者(占样本的73%)进行了调查。自我报告的慢性咳嗽总体患病率为6.3%[95%置信区间(CI):5.0 - 7.6%]。女性性别、年龄、身高、体重指数和吸烟与咳嗽显著相关。此外,鼻塞、鼻分泌物、打喷嚏、哮喘、气味和冷空气敏感性以及阿司匹林不耐受也与咳嗽有统计学意义的关联,表明慢性咳嗽与上呼吸道症状之间存在密切联系。与其他研究一致,本研究表明慢性咳嗽在社会中是一个普遍存在的问题,在女性中的发生率约为男性的两倍。