印度尼西亚北苏拉威西省慢性肝病患者和健康对照人群中的乙型肝炎病毒感染情况。
Hepatitis B virus infection in patients with chronic liver disease and healthy controls in north-Sulawesi, Indonesia.
作者信息
Wolff A P, Ruys A H, Dolmans W M, Van Loon A M, Pangalila P F
机构信息
Department of Tropical Medicine, St. Radboud University Hospital, Nijmegen, The Netherlands.
出版信息
Trop Geogr Med. 1990 Jul;42(3):221-5.
Markers of hepatitis-B virus (HBV) infection were determined in 42 patients with chronic liver disease (CLD) and in 42 age and sex matched healthy controls. At least one marker for HBV was found in 38 patients (90%) and in 29 controls (69%). HBsAg was present in 29 patients (69%) as opposed to 14 controls (33%; p less than 0.001). The very high prevalence of HBV infection, the significant difference with respect to HBV markers, particularly HBsAg, between patients and controls and in particular the high percentage of healthy HBV-carriers poses a considerable risk to the population of North-Sulawesi and stresses the need for HBV-vaccination.
对42例慢性肝病（CLD）患者以及42例年龄和性别相匹配的健康对照者进行了乙肝病毒（HBV）感染标志物检测。在38例患者（90%）和29例对照者（69%）中发现了至少一种HBV标志物。29例患者（69%）存在乙肝表面抗原（HBsAg），而对照者中有14例（33%）存在HBsAg（p<0.001）。HBV感染的极高患病率、患者与对照者之间HBV标志物（尤其是HBsAg）的显著差异，特别是健康HBV携带者的高比例，对北苏拉威西岛的人群构成了相当大的风险，并强调了HBV疫苗接种的必要性。
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