Ibia E O, Asindi A A
Department of Paediatrics, University of Calabar Teaching Hospital, Nigeria.
Trop Geogr Med. 1990 Jul;42(3):226-32.
Children admitted with measles to the University of Calabar Teaching Hospital, Calabar, Nigeria, were studied to determine the influence of the Expanded Programme on Immunization (EPI), launched in Nigeria in 1984. The data suggest a downward trend in the overall incidence of measles in the first 4 years of the campaign. However, compared with a previous study period (June 1981 to May 1983) in the same institution, the proportion of measles victims aged below 9 months had increased from 15 to 21 percent and the overall death rate had increased sevenfold. Delay in administering the measles vaccine (9 instead of 6 months) and the deteriorating nutritional status of Nigerian children probably account for this negative impact. The advantages of altering the immunization age for measles from 6 to 9 months have not been fully established in Nigeria yet.
对尼日利亚卡拉巴尔大学教学医院收治的麻疹患儿进行了研究，以确定1984年在尼日利亚启动的扩大免疫规划（EPI）的影响。数据表明，在该活动开展的前四年，麻疹总体发病率呈下降趋势。然而，与同一机构之前的研究时期（1981年6月至1983年5月）相比，9个月以下麻疹患儿的比例从15%上升至21%，总体死亡率上升了七倍。麻疹疫苗接种延迟（9个月而非6个月）以及尼日利亚儿童营养状况恶化可能是造成这种负面影响的原因。在尼日利亚，将麻疹免疫年龄从6个月改为9个月的益处尚未完全明确。
