Guessous I, Bochud M
Unité d'épidémiologie populationnelle, Département de médecine communautaire, de premier recours et des urgences, HUG, 1211 Genève 14.
Rev Med Suisse. 2012 Jul 11;8(348):1458-63.
Studies exploring the effect of calcium supplementation on cardiovascular risk suggest that systolic blood pressure decreases with supplementation. A lower calcium intake has been associated with an increased risk of stroke. By contrast, calcium supplementation may increase the risk of myocardial infarction. The effect of vitamin D supplementation on blood pressure is still unclear and no effect of vitamin D supplementation on coronary heart disease or stroke has been clearly demonstrated. There is a lack of randomized clinical trials primarily addressing the effect of these parameters on CVD. Currently, the use of calcium and vitamin D supplementations for the prevention of cardiovascular disease is not justified.
探索补钙对心血管风险影响的研究表明，补钙会使收缩压降低。钙摄入量较低与中风风险增加有关。相比之下，补钙可能会增加心肌梗死的风险。补充维生素D对血压的影响仍不明确，且补充维生素D对冠心病或中风的影响尚未得到明确证实。主要针对这些参数对心血管疾病影响的随机临床试验较少。目前，使用钙和维生素D补充剂预防心血管疾病是不合理的。
