Allais Gianni, Castagnoli Gabellari Ilaria, Mana Ornella, Benedetto Chiara
Women's Headache Center, Department of Gynecology & Obstetrics, University of Turin, Turin, Italy.
Womens Health (Lond). 2012 Sep;8(5):529-41. doi: 10.2217/whe.12.37.
Approximately 50% of migrainous women suffer from menstrually related migraine (MRM), a type of migraine in which the attacks occur at the same time as or near the menstrual flow. Attacks of MRM tend to be longer, more intense and disabling and sometimes less responsive to treatment than non-menstrual migraines. Similar to the management of non-menstrual migraine, the use of triptans and NSAIDs is the gold standard for MRM treatment. In this paper, the most important studies in the literature that report the effectiveness of triptans, of certain associated drugs and other analgesic agents are summarized. Preventive strategies that can be used if a prophylactic treatment is needed is also analyzed, with particular attention paid to the use of perimenstrual prophylaxis with triptans and/or NSAIDs. Moreover, considering the peculiar interaction between menstrual migraine and female sex hormones, brief mention is made to possible hormonal manipulations.
约50%的偏头痛女性患有月经相关性偏头痛（MRM），这是一种偏头痛类型，其发作与月经来潮同时或接近月经来潮时发生。与非月经性偏头痛相比，MRM发作往往持续时间更长、更剧烈且使人丧失能力，有时对治疗的反应也较差。与非月经性偏头痛的治疗类似，使用曲坦类药物和非甾体抗炎药是MRM治疗的金标准。本文总结了文献中报道曲坦类药物、某些相关药物及其他镇痛药有效性的最重要研究。还分析了在需要预防性治疗时可采用的预防策略，特别关注在月经周期使用曲坦类药物和/或非甾体抗炎药进行预防性治疗。此外，考虑到月经性偏头痛与女性性激素之间的特殊相互作用，简要提及了可能的激素调控方法。
