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运动和茶儿茶素对社区居住的日本老年女性肌肉减少症患者肌肉量、力量和行走能力的影响:一项随机对照试验。

Effects of exercise and tea catechins on muscle mass, strength and walking ability in community-dwelling elderly Japanese sarcopenic women: a randomized controlled trial.

机构信息

Research Team for Promoting Independence of the Elderly, Tokyo Metropolitan Institute of Gerontology, Tokyo, Japan.

出版信息

Geriatr Gerontol Int. 2013 Apr;13(2):458-65. doi: 10.1111/j.1447-0594.2012.00923.x. Epub 2012 Aug 31.

Abstract

AIM

To investigate the effects of exercise and/or tea catechin supplementation on muscle mass, strength and walking ability in elderly Japanese women with sarcopenia.

METHODS

A total of 128 women aged over 75 years were defined as sarcopenic and randomly assigned into four groups: exercise and tea catechin supplementation (n = 32), exercise (n = 32), tea catechin supplementation (n = 32) or health education (n = 32). The exercise group attended a 60-min comprehensive training program twice a week and the tea catechin supplementation group ingested 350 mL of a tea beverage fortified with catechin daily for 3 months. Body composition was determined by bioelectrical impedance analysis. Interview data and functional fitness measurements, such as muscle strength, balance and walking ability, were collected at baseline and after the 3-month intervention.

RESULTS

There were significant group × time interactions observed in timed up & go (P < 0.001), usual walking speed (P = 0.007) and maximum walking speed (P < 0.001). The exercise + catechin group showed a significant effect (odds ratio 3.61, 95% confidence interval 1.05-13.66) for changes in the combined variables of leg muscle mass and usual walking speed compared with the health education group.

CONCLUSIONS

The combination of exercise and tea catechin supplementation had a beneficial effect on physical function measured by walking ability and muscle mass.

摘要

目的

研究运动和/或茶儿茶素补充对患有肌肉减少症的日本老年女性肌肉量、力量和步行能力的影响。

方法

共纳入 128 名年龄在 75 岁以上的女性,定义为肌肉减少症患者,并随机分为四组:运动和茶儿茶素补充组(n=32)、运动组(n=32)、茶儿茶素补充组(n=32)和健康教育组(n=32)。运动组每周参加 2 次 60 分钟的综合训练计划,茶儿茶素补充组每天摄入 350 毫升强化儿茶素的茶饮料,持续 3 个月。采用生物电阻抗分析法测定身体成分。在基线和 3 个月干预后收集访谈数据和功能适应性测试结果,如肌肉力量、平衡和步行能力。

结果

在计时起立行走(P<0.001)、日常行走速度(P=0.007)和最大行走速度(P<0.001)方面,组间存在显著的时间交互作用。运动+儿茶素组与健康教育组相比,腿部肌肉量和日常行走速度综合变量的变化有显著的效果(比值比 3.61,95%置信区间 1.05-13.66)。

结论

运动和茶儿茶素补充的联合应用对步行能力和肌肉量等身体功能有有益影响。

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