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为国家骨髓捐赠项目招募非亲属捐赠者。

Recruiting unrelated donors for the National Marrow Donor Program.

作者信息

Yanke D R

机构信息

Connecticut Red Cross Blood Services, Farmington.

出版信息

Yale J Biol Med. 1990 Sep-Oct;63(5):509-14.

PMID:2293510
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC2589373/
Abstract

Medical advances have made bone marrow transplantation the treatment of choice for certain hematologic diseases. For those patients eligible for a marrow transplant only about 30 percent find an HLA-compatible match within their families. Studies indicate that unrelated volunteers are willing to donate their marrow. The National Marrow Donor Program was formed in 1986 as a result of a federal contract. This group is a network of donor centers, transplant centers, and collection centers. The Connecticut Red Cross Blood Services is one of approximately 70 donor centers. Recruitment methods vary with each donor center, depending on the resources available. The Connecticut Red Cross Blood Services has recruited more than 1,000 volunteers for entry into the National Marrow Donor Program.

摘要

医学进步已使骨髓移植成为某些血液疾病的首选治疗方法。对于那些有资格接受骨髓移植的患者来说,只有约30%的人能在其家族中找到人类白细胞抗原(HLA)匹配的供体。研究表明,非亲属志愿者愿意捐献他们的骨髓。国家骨髓捐赠项目是1986年一项联邦合同的产物。该组织是一个由捐赠中心、移植中心和采集中心组成的网络。康涅狄格州红十字会血液服务中心是约70个捐赠中心之一。招募方法因每个捐赠中心而异,这取决于可用资源。康涅狄格州红十字会血液服务中心已招募了1000多名志愿者加入国家骨髓捐赠项目。

相似文献

1
Recruiting unrelated donors for the National Marrow Donor Program.为国家骨髓捐赠项目招募非亲属捐赠者。
Yale J Biol Med. 1990 Sep-Oct;63(5):509-14.
2
Unrelated-donor marrow transplants: the experience of the National Marrow Donor Program.非亲缘供者骨髓移植:国家骨髓供者计划的经验
Clin Transpl. 1994:295-301.
3
Past and future of providing matched, unrelated donors for marrow transplantation.为骨髓移植提供匹配的非亲属供者的过去与未来。
Ann Clin Lab Sci. 1997 Sep-Oct;27(5):346-50.
4
The U.S. National Marrow Donor Program.美国国家骨髓捐献项目。
Am J Pediatr Hematol Oncol. 1994 Feb;16(1):30-4.
5
The National Marrow Donor Program: how it works, accomplishments to date.国家骨髓捐赠计划:其运作方式及迄今取得的成就。
Oncology (Williston Park). 1989 Feb;3(2):63-8, 72; discussion 72-4.
6
Quality control of a national bone marrow donor registry: results of a pilot study and proposal for a standardized approach.国家骨髓捐献者登记处的质量控制:一项试点研究的结果及标准化方法建议
Bone Marrow Transplant. 2003 Sep;32(6):623-7. doi: 10.1038/sj.bmt.1704229.
7
The national marrow donor program 20 years of unrelated donor hematopoietic cell transplantation.国家骨髓捐赠计划20年非血缘供者造血细胞移植。
Biol Blood Marrow Transplant. 2008 Sep;14(9 Suppl):2-7. doi: 10.1016/j.bbmt.2008.05.017.
8
Marrow transplants from HLA matched unrelated donors: an NMDP update and the Seattle experience.来自人类白细胞抗原(HLA)匹配的无关供者的骨髓移植:国家骨髓捐赠计划(NMDP)的最新情况及西雅图的经验
Bone Marrow Transplant. 1994 Jun;13(6):693-5.
9
[Search for bone marrow donors for patients with hematologic-oncologic diseases].
Beitr Infusionsther. 1990;26:214-6.
10
Bone marrow transplantation with unrelated donors: what is the probability of identifying an HLA-A/B/Cw/DRB1/B3/B5/DQB1-matched donor?非亲缘供者骨髓移植:找到一位HLA-A/B/Cw/DRB1/B3/B5/DQB1配型相合供者的概率是多少?
Bone Marrow Transplant. 2000 Aug;26(4):437-41. doi: 10.1038/sj.bmt.1702529.

本文引用的文献

1
Bone marrow transplantation from unrelated volunteer donors: summary of a conference on scientific, ethical, legal, financial, and other practical issues.来自非亲属志愿捐赠者的骨髓移植:关于科学、伦理、法律、财务及其他实际问题的会议总结
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Transplantation of marrow from an unrelated donor to a patient with acute leukemia.
N Engl J Med. 1980 Sep 4;303(10):565-7. doi: 10.1056/NEJM198009043031007.
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On willingness to be a bone marrow donor.
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A prospective study of androgens and bone marrow transplantation for treatment of severe aplastic anemia.雄激素与骨髓移植治疗重型再生障碍性贫血的前瞻性研究。
Blood. 1979 Mar;53(3):504-14.
6
Severe combined immunodeficiency disease. Characterization of the disease and results of transplantation.
JAMA. 1977 Aug 15;238(7):591-600.