Department of Medicine, Division of Geriatric Medicine and Gerontology, School of Medicine, Johns Hopkins University, Baltimore, Maryland, USA.
Am J Epidemiol. 2012 Sep 15;176(6):534-43. doi: 10.1093/aje/kws125. Epub 2012 Aug 30.
Few studies have addressed changes in physical activity participation over time among the elderly. The authors hypothesized that there were distinct trajectories of physical activity level over time and identifiable predictors of such trajectories, as well as that the maintenance of regular physical activity, even below recommended levels, was associated with lower mortality risk. Using longitudinal data (1994-2009) from 433 initially high-functioning older women aged 70-79 years at baseline, a joint latent class and survival mixture model identified 4 activity trajectory classes: always active (16.6%), fast declining (19.2%), stable moderate (32.3%), and always sedentary (31.9%). Obesity, coronary artery disease, chronic obstructive pulmonary disease, depressive symptoms, low self-efficacy, mobility disability, and low energy were associated with sedentary behavior and/or a fast decline in activity. Women in the fast declining and always sedentary classes had hazard ratios for death of 2.34 (95% confidence interval: 1.20, 4.59) and 3.34 (95% confidence interval: 1.72, 6.47), respectively, compared with the always active class; no mortality difference was found between the stable moderate and always active groups (hazard ratio = 1.24, 95% confidence interval: 0.63, 2.47). Our findings suggest that physical activity does not have to be vigorous to be beneficial and that the gain may be the greatest among women who reported the lowest levels of activity.
很少有研究关注老年人随时间推移的身体活动参与变化。作者假设,身体活动水平随时间存在明显的轨迹,并且可以识别出这些轨迹的预测因素,此外,即使低于推荐水平,保持有规律的身体活动也与较低的死亡率风险相关。利用基线时年龄为 70-79 岁的 433 名最初功能较高的老年女性(1994-2009 年)的纵向数据,联合潜在类别和生存混合模型确定了 4 种活动轨迹类别:始终活跃(16.6%)、快速下降(19.2%)、稳定适度(32.3%)和始终久坐(31.9%)。肥胖、冠状动脉疾病、慢性阻塞性肺疾病、抑郁症状、低自我效能、移动障碍和低能量与久坐行为和/或活动快速下降相关。与始终活跃组相比,快速下降组和始终久坐组的女性死亡风险比分别为 2.34(95%置信区间:1.20,4.59)和 3.34(95%置信区间:1.72,6.47);稳定适度组和始终活跃组之间未发现死亡率差异(风险比=1.24,95%置信区间:0.63,2.47)。我们的研究结果表明,身体活动不必剧烈就能带来益处,而对于报告活动水平最低的女性,获益可能最大。