Department of Physical Therapy, Rehabilitation Sciences Division, University of Texas Medical Branch, Galveston, Texas.
J Head Trauma Rehabil. 2013 Sep-Oct;28(5):E13-20. doi: 10.1097/HTR.0b013e31826463a1.
The purpose of this study was to compare the peak aerobic capacities and ventilatory anaerobic thresholds (VAT) of individuals with a traumatic brain injury (TBI) to age- and gender-matched controls.
Nineteen participants that previously suffered a mild to moderate TBI and 19 apparently healthy controls volunteered as subjects. Traumatic brain injury and healthy controls were matched for age and gender and were similar in weight and body mass index. Volunteers performed a maximal graded treadmill test to volitional failure where oxygen consumption ((Equation is included in full-text article.)O2), carbon dioxide production ((Equation is included in full-text article.)CO2, ventilation ((Equation is included in full-text article.)E, and heart rate were measured continuously. From metabolic and ventilatory data, VAT was measured using a previously described method. VAT and peak exercise responses of participants with a TBI were compared with healthy controls.
The (Equation is included in full-text article.)O2, and (Equation is included in full-text article.)CO2 at VAT and peak exercise were lower for TBI compared with healthy controls. (Equation is included in full-text article.)E was also lower for TBI at VAT and peak exercise. Heart rate was lower for TBI at VAT; however, TBI had similar heart rate to healthy controls at peak exercise.
The VAT and peak exercise capacities of participants with a TBI were below the metabolic demands of many routine daily activities. The data suggest that therapeutic interventions for individuals with a TBI should include targeted exercise prescriptions to improve cardiorespiratory fitness.
本研究旨在比较创伤性脑损伤（TBI）患者与年龄和性别匹配的对照组个体的峰值有氧能力和通气无氧阈（VAT）。
19 名曾患有轻度至中度 TBI 的参与者和 19 名明显健康的对照自愿作为研究对象。TBI 和健康对照组在年龄和性别上相匹配，体重和体重指数也相似。志愿者进行了最大递增跑步机测试，直至自愿衰竭，在此过程中连续测量耗氧量（(Equation is included in full-text article.)O2）、二氧化碳产量（(Equation is included in full-text article.)CO2）、通气量（(Equation is included in full-text article.)E）和心率。根据代谢和通气数据，使用先前描述的方法测量 VAT。将 TBI 患者的 VAT 和峰值运动反应与健康对照组进行比较。
与健康对照组相比，TBI 在 VAT 和峰值运动时的(Equation is included in full-text article.)O2 和(Equation is included in full-text article.)CO2 较低。TBI 在 VAT 和峰值运动时的(E)也较低。TBI 在 VAT 时的心率较低；然而，TBI 在峰值运动时的心率与健康对照组相似。
TBI 患者的 VAT 和峰值运动能力低于许多日常活动的代谢需求。数据表明，针对 TBI 患者的治疗干预措施应包括有针对性的运动处方，以提高心肺适应能力。
