Chin Lisa M K, Chan Leighton, Woolstenhulme Joshua G, Christensen Eric J, Shenouda Christian N, Keyser Randall E
Department of Rehabilitation Science, George Mason University, Fairfax, Virginia (Drs Chin, Woolstenhulme, and Keyser); and Rehabilitation Medicine Department, National Institutes of Health Clinical Center (Drs Chin, Chan, Woolstenhulme, and Keyser and Mr Christensen), and Center for Neuroscience and Regenerative Medicine (Drs Chan and Shenouda), Bethesda, Maryland.
J Head Trauma Rehabil. 2015 Nov-Dec;30(6):382-90. doi: 10.1097/HTR.0000000000000062.
To examine cardiorespiratory fitness in individuals with traumatic brain injury (TBI), before and following participation in a supervised 12-week aerobic exercise training program.
Ten subjects with nonpenetrating TBI (TBI severity: mild, 50%; moderate, 40%; severe, 10%; time since injury [mean ± SD]: 6.6 ± 6.8 years) performed exercise training on a treadmill 3 times a week for 30 minutes at vigorous intensity (70%-80% of heart rate reserve). All subjects completed a cardiopulmonary exercise test, with pulmonary gas exchange measured and a questionnaire related to fatigue (Fatigue Severity Scale) at baseline and following exercise training.
After training, increases (P < .01) in peak oxygen consumption ((Equation is included in full-text article.); +3.1 ± 2.4 mL/min/kg), time to volitional fatigue (+1.4 ± 0.8 minutes), and peak work rate (+59 ± 43 W) were observed. At the anaerobic threshold, (Equation is included in full-text article.)(+3.6 ± 2.1 mL/kg/min), treadmill time (+1.8 ± 1.1 minutes), and work rate (+37 ± 39 W) were higher (P < .01) following exercise training. Subjects also reported significantly lower (P < .05) Fatigue Severity Scale composite scores (-0.9 ± 1.3) following exercise training.
These findings suggest that individuals with TBI may benefit from participation in vigorous aerobic exercise training with improved cardiorespiratory fitness and diminished fatigue.
研究创伤性脑损伤（TBI）患者在参加为期12周的有监督的有氧运动训练计划之前和之后的心肺适能。
10名非穿透性TBI患者（TBI严重程度：轻度，50%；中度，40%；重度，10%；受伤时间[均值±标准差]：6.6±6.8年）每周在跑步机上进行3次运动训练，每次30分钟，强度为剧烈（心率储备的70%-80%）。所有受试者在基线和运动训练后均完成了心肺运动测试，测量了肺气体交换，并填写了一份与疲劳相关的问卷（疲劳严重程度量表）。
训练后，观察到峰值耗氧量（（公式包含在全文中）；增加3.1±2.4毫升/分钟/千克）、意志疲劳时间（增加1.4±0.8分钟）和峰值工作率（增加59±43瓦）均有增加（P<.01）。在无氧阈值时，（公式包含在全文中）（增加3.6±2.1毫升/千克/分钟）、跑步机运动时间（增加1.8±1.1分钟）和工作率（增加37±39瓦）在运动训练后更高（P<.01）。受试者还报告说，运动训练后疲劳严重程度量表综合评分显著降低（P<.05）（降低0.9±1.3）。
这些发现表明，TBI患者可能受益于参加剧烈有氧运动训练，从而改善心肺适能并减轻疲劳。
