Kajbafzadeh Abdol-Mohammad, Harsini Sara, Baghayee Arash, Javan-Farazmand Niloufar
Pediatric Urology Research Center, Department of Pediatric Urology, Children's Hospital Medical Center, Tehran University of Medical Sciences, Tehran, Iran.
J Pediatr Hematol Oncol. 2013 Apr;35(3):e109-11. doi: 10.1097/MPH.0b013e31826683a8.
Wilms tumor (WT) is described as a component of many different clinical conditions and genetic syndromes. However, the simultaneous occurrence of WT and a duplex collecting system is extremely rare. We report a case of a 4-year-old boy diagnosed with WT and a left duplex collecting system. The patient underwent a left radical nephrectomy. The histologic examination diagnosed it to be a case of WT with favorable histology. The patient received the chemotherapy regimen for stage 1 WT and was in complete remission during the follow-up period of 2 years. Further investigations are required for assessing the need for screening of WT in children with genitourinary malformations.
肾母细胞瘤（WT）被认为是许多不同临床病症和遗传综合征的一个组成部分。然而，WT与双肾盂收集系统同时出现的情况极为罕见。我们报告一例4岁男孩，被诊断为患有WT和左侧双肾盂收集系统。该患者接受了左侧根治性肾切除术。组织学检查诊断为组织学表现良好的WT病例。该患者接受了1期WT的化疗方案，在2年的随访期内完全缓解。对于评估患有泌尿生殖系统畸形的儿童是否需要进行WT筛查，还需要进一步研究。
