无透镜成像：宽场片上显微镜的成就和待解决的挑战。
Imaging without lenses: achievements and remaining challenges of wide-field on-chip microscopy.
机构信息
Electrical Engineering Department, University of California, Los Angeles, Los Angeles, California, USA.
出版信息
Nat Methods. 2012 Sep;9(9):889-95. doi: 10.1038/nmeth.2114. Epub 2012 Aug 30.
Abstract
We discuss unique features of lens-free computational imaging tools and report some of their emerging results for wide-field on-chip microscopy, such as the achievement of a numerical aperture (NA) of ∼0.8-0.9 across a field of view (FOV) of more than 20 mm(2) or an NA of ∼0.1 across a FOV of ∼18 cm(2), which corresponds to an image with more than 1.5 gigapixels. We also discuss the current challenges that these computational on-chip microscopes face, shedding light on their future directions and applications.
摘要
我们讨论了无透镜计算成像工具的独特特点，并报告了它们在宽场片上显微镜方面的一些新兴结果，例如在超过 20mm² 的视场中实现了约 0.8-0.9 的数值孔径（NA），或者在约 18cm² 的视场中实现了约 0.1 的 NA，这对应于具有超过 1.5 亿像素的图像。我们还讨论了这些计算片上显微镜目前面临的挑战，为它们的未来方向和应用提供了思路。
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