Department of Chemistry and Molecular-Level Interface Research Center, Korea Advanced Institute of Science and Technology (KAIST), Daejeon, Korea.
Angew Chem Int Ed Engl. 2012 Sep 24;51(39):9904-8. doi: 10.1002/anie.201205723. Epub 2012 Aug 31.
No muss, no fuss: A rhodium-catalyzed direct intermolecular C-H amination of benzamides and ketoximes using aryl azides as the amine source has been developed. The reaction exhibits a broad substrate scope with excellent functional-group tolerance, requires no external oxidants, releases N(2) as the only by-product, and produces diarylamines in high yields.
已开发出一种铑催化的酰胺和酮肟的直接分子间 C-H 胺化反应，使用芳基叠氮化物作为胺源。该反应具有广泛的底物范围，对官能团具有优异的耐受性，不需要外部氧化剂，仅释放氮气作为唯一的副产物，并以高产率得到二芳基胺。
