Awad Amer, Estephan Bachir, Stüve Olaf
Baton Rouge Neurology Associates, Baton Rouge General Medical Center, 3600 Florida Boulevard, Baton Rouge, LA 70806, USA.
Case Rep Neurol Med. 2011;2011:515182. doi: 10.1155/2011/515182. Epub 2011 Sep 7.
Intravascular lymphoma is a rare but well-described entity. The clinical manifestations are heterogeneous. We report a case of a 59-year-old woman who presented initially with syncope followed by subacute cognitive decline that progressed to minimally conscious state. Shortly after the transfer to our tertiary center the patient died. Brain autopsy disclosed the diagnosis of B-cell intravascular lymphoma. We speculate that syncope could be the first manifestation of central nervous system intravascular lymphoma and should be considered in the differential diagnosis of unexplained syncope. In addition, we stress the importance of early brain biopsy in unexplained white matter disease.
血管内淋巴瘤是一种罕见但已得到充分描述的疾病。其临床表现具有异质性。我们报告一例59岁女性病例，该患者最初表现为晕厥，随后出现亚急性认知功能衰退，进而发展为最低意识状态。转至我们的三级医疗中心后不久，患者死亡。脑部尸检确诊为B细胞血管内淋巴瘤。我们推测晕厥可能是中枢神经系统血管内淋巴瘤的首发表现，在不明原因晕厥的鉴别诊断中应予以考虑。此外，我们强调对不明原因白质疾病进行早期脑活检的重要性。
