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延迟诊断:相互矛盾的检查结果应受到质疑。

A delayed diagnosis: conflicting investigation results should be challenged.

作者信息

Mital D, Desai V

机构信息

Department of Sexual Health and HIV Medicine, Milton Keynes NHS Foundation Trust, Standing Way, Milton Keynes MK6 5LD, UK.

出版信息

Case Rep Pathol. 2011;2011:809567. doi: 10.1155/2011/809567. Epub 2011 Sep 22.

DOI:10.1155/2011/809567
PMID:22937394
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC3420495/
Abstract

We present a case where a diagnosis of advanced HIV led to many other diagnoses but more importantly life-threatening multivariant Castleman's disease which is rare and was successfully treated. This case highlights the importance of questioning and challenging investigations when it does not fit with the clinical picture. Multidisciplinary teams are crucial and always seek expert advice if unsure. The much-quoted adage of "many symptoms and signs will fit one diagnosis" also bodes well in this case.

摘要

我们报告了一例晚期艾滋病病例,该病例引发了许多其他诊断,但更重要的是引发了罕见的、危及生命的多型性Castleman病,而该疾病已得到成功治疗。该病例凸显了在检查结果与临床表现不符时进行质疑和挑战的重要性。多学科团队至关重要,如有疑问应始终寻求专家建议。“多种症状和体征可能符合一种诊断”这句常被引用的格言在本病例中也得到了很好的体现。

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A delayed diagnosis: conflicting investigation results should be challenged.延迟诊断:相互矛盾的检查结果应受到质疑。
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A Case Report of Subclinical Myasthenia Gravis Associated with Castleman's Disease.一例副肿瘤性肌萎缩症伴发 Castleman 病 **解析**: - “A Case Report of Subclinical Myasthenia Gravis Associated with Castleman's Disease.”:直译为“副肿瘤性肌萎缩症伴发 Castleman 病的病例报告”,为了更符合中文表达习惯,调整语序为“一例副肿瘤性肌萎缩症伴发 Castleman 病”。 - “Subclinical Myasthenia Gravis”:直译为“副肿瘤性肌萎缩症”,保留英文简称。 - “Castleman's Disease”:直译为“Castleman 病”,保留英文简称。
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本文引用的文献

1
Castleman disease in the 21st century: an update on diagnosis, assessment, and therapy.21世纪的Castleman病:诊断、评估及治疗的最新进展
Clin Adv Hematol Oncol. 2010 Jul;8(7):486-98.
2
Highly active antiretroviral therapy alone may be an effective treatment for HIV-associated multi-centric Castleman's disease.仅高效抗逆转录病毒疗法可能是治疗HIV相关多中心Castleman病的有效方法。
Haematologica. 2010 Nov;95(11):1979-81. doi: 10.3324/haematol.2010.027441. Epub 2010 Aug 26.
3
Multicentric Castleman's disease & HIV infection.多中心性Castleman病与HIV感染。
Ir Med J. 2009 Oct;102(9):294-5.
4
The role of immune suppression and HHV-8 in the increasing incidence of HIV-associated multicentric Castleman's disease.免疫抑制和人疱疹病毒8型在人类免疫缺陷病毒相关多中心Castleman病发病率上升中的作用
Ann Oncol. 2009 Apr;20(4):775-9. doi: 10.1093/annonc/mdn697. Epub 2009 Jan 29.
5
Multicentric Castleman's disease in HIV infection.HIV感染中的多中心性Castleman病
Int J STD AIDS. 2006 Jan;17(1):19-24; quiz 25. doi: 10.1258/095646206775220496.