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酷似强直性脊柱炎的播散性结核病。

Disseminated tuberculosis mimicking ankylosing spondylitis.

作者信息

Huyge Valérie, Goldman Serge, Soyfoo Muhammad S

机构信息

Department of Nuclear Medicine, Hôpital Erasme, Université Libre de Bruxelles (ULB), 1070 Brussels, Belgium.

出版信息

Case Rep Rheumatol. 2011;2011:195085. doi: 10.1155/2011/195085. Epub 2011 Sep 6.

DOI:10.1155/2011/195085
PMID:22937440
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC3420786/
Abstract

Ankylosing spondylitis is a chronic inflammatory disorder affecting mainly the axial skeleton. Here we report a case of a man with a clinical suspicion of ankylosing spondylitis but with a persistence of increased inflammatory markers. In this case, (18)F-FDG-PET/CT revealed multiple hypermetabolic lesions in axial skeleton, lymph nodes, and the lung, suggestive of either disseminated tuberculosis or lymphoma. Histological analysis of the pulmonary lesion revealed mycobacterium tuberculosis. This case highlights, firstly, the importance of excluding other diagnoses in the presence of clinical picture of ankylosing spondylitis and high inflammatory markers and, secondly, the determining role of PET/CT.

摘要

强直性脊柱炎是一种主要影响中轴骨骼的慢性炎症性疾病。在此，我们报告一例临床怀疑为强直性脊柱炎但炎症标志物持续升高的男性病例。在该病例中，（18）F-FDG-PET/CT显示中轴骨骼、淋巴结和肺部有多个高代谢病灶，提示播散性结核或淋巴瘤。肺部病灶的组织学分析显示为结核分枝杆菌。该病例首先强调了在强直性脊柱炎临床表现和高炎症标志物存在的情况下排除其他诊断的重要性，其次强调了PET/CT的决定性作用。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/7908/3420786/21d3d31431f0/CRIM.RHEUMATOLOGY2011-195085.003.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/7908/3420786/a1ba56e22171/CRIM.RHEUMATOLOGY2011-195085.001.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/7908/3420786/23137c89fade/CRIM.RHEUMATOLOGY2011-195085.002.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/7908/3420786/21d3d31431f0/CRIM.RHEUMATOLOGY2011-195085.003.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/7908/3420786/a1ba56e22171/CRIM.RHEUMATOLOGY2011-195085.001.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/7908/3420786/23137c89fade/CRIM.RHEUMATOLOGY2011-195085.002.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/7908/3420786/21d3d31431f0/CRIM.RHEUMATOLOGY2011-195085.003.jpg

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