Itsukaichi Mina, Takakuwa Koichi, Yamaguchi Masayuki, Serikawa Takehiro, Tanaka Kenichi, Kojima Kinuko, Sakakibara Seiichi, Usuda Tohei, Matsunaga Masamichi, Hashimoto Tsuyoshi
Department of Obstetrics and Gynecology, Niigata University Medical and Dental Hospital, Niigata City, Japan.
Pediatr Dermatol. 2013 Jul-Aug;30(4):e59-60. doi: 10.1111/j.1525-1470.2012.01828.x. Epub 2012 Sep 3.
Dichorionic diamniotic twins were born at 37 weeks of gestation by cesarean section to a 34-year-old primigravid Japanese woman because the first twin was in breech presentation. The mother had been diagnosed with pemphigus vulgaris prior to her pregnancy. In addition to a high antidesmoglein 3 autoantibody titer, flaccid bullae and erosions on both of the twins' lips and in their oral cavities at 13 days of age led to the diagnosis of neonatal pemphigus vulgaris. This case highlights the need for awareness that pemphigus vulgaris may not occur immediately after birth.
双绒毛膜双羊膜囊双胞胎在孕37周时通过剖宫产出生,母亲是一名34岁的初产妇,为日本女性,因为第一对双胞胎是臀位。母亲在怀孕前被诊断为寻常型天疱疮。除了抗桥粒芯糖蛋白3自身抗体滴度高外,双胞胎在13日龄时嘴唇和口腔出现松弛性水疱和糜烂,导致诊断为新生儿寻常型天疱疮。该病例强调了需要认识到寻常型天疱疮可能不会在出生后立即出现。