Kung A W, Pun K K, Lam K, Wang C, Leung C Y
Department of Medicine, University of Hong Kong.
Cancer. 1990 Jan 1;65(1):177-9. doi: 10.1002/1097-0142(19900101)65:1<177::aid-cncr2820650134>3.0.co;2-8.
Metastases to the adrenal glands are common in patients with malignancy but malignant disease presenting as Addisonian crisis is rare. The authors presented two patients with acute Addisonian crises due to metastatic infiltration of the adrenal glands. They were otherwise asymptomatic from the primary tumor. Computed tomographic scan showed bilateral adrenal enlargement and transcutaneous biopsy confirmed metastatic adenocarcinoma in the adrenals. Adequate glucocorticoid replacement improves quality of life and prolongs survival.
肾上腺转移在恶性肿瘤患者中很常见，但以艾迪生病危象为表现的恶性疾病却很少见。作者报告了两名因肾上腺转移浸润而出现急性艾迪生病危象的患者。他们原发性肿瘤方面并无其他症状。计算机断层扫描显示双侧肾上腺肿大，经皮活检证实肾上腺存在转移性腺癌。充足的糖皮质激素替代治疗可改善生活质量并延长生存期。
