Berg S L, Phebus C K, Wenger S L
Division of Hematology/Oncology, University of Pittsburgh, School of Medicine, Pennsylvania.
Cancer Genet Cytogenet. 1990 Jan;44(1):55-9. doi: 10.1016/0165-4608(90)90197-i.
A case of a boy with juvenile chronic myelogenous leukemia (CML) and independent clonal abnormalities of chromosomes 4 and 5 is presented. The characteristics and cytogenetics of CML are discussed, as is the involvement of chromosomes 4 and 5 in hematologic malignancies. The significance of these karyotypic findings in juvenile CML is explored.
