Department of Neuroscience and Imaging, University "G. d'Annunzio" Chieti-Pescara, Italy.
Cortex. 2013 Jan;49(1):336-9. doi: 10.1016/j.cortex.2012.07.002. Epub 2012 Aug 14.
In thalamic lesions a pseudocortical syndrome has been occasionally described but the effect of the lesion on the cortical network of tactile recognition has never been studied. We report a patient who developed tactile agnosia in the left hand after right thalamic stroke, configuring a pseudocortical sensory syndrome. The discriminative sensory dysfunction was dissociate because only tactile agnosia and mild pseudoathetosis were present. A functional magnetic resonance imaging (fMRI) study showed that tactile recognition with the unaffected hand recruited a bilateral fronto-parietal network. During recognition with the left hand the activation was restricted and lateralized to the ipsilateral hemisphere. In this patient with pseudocortical discriminative sensory dysfunction the lack of activation of the whole cortical network, implicated in tactile recognition, demonstrates that pseudocortical is functionally equivalent to cortical tactile agnosia.
在丘脑病变中，偶尔会描述一种假性皮质综合征，但病变对触觉识别的皮质网络的影响从未被研究过。我们报告了一例右侧丘脑卒中后左手出现触觉失认的患者，构成了一种假性皮质感觉综合征。感觉辨别功能障碍是分离的，因为只有触觉失认和轻度假性手足徐动症存在。功能性磁共振成像 (fMRI) 研究表明，使用未受影响的手进行触觉识别会募集双侧额顶叶网络。在使用左手进行识别时，激活受到限制并偏向同侧半球。在这位患有假性皮质辨别感觉功能障碍的患者中，涉及触觉识别的整个皮质网络的激活缺失表明，假性皮质在功能上等同于皮质性触觉失认。
