Department of Obstetrics and Gynecology, Feinberg School of Medicine, Northwestern University, Chicago, IL 60611, USA.
Am J Obstet Gynecol. 2012 Nov;207(5):401.e1-6. doi: 10.1016/j.ajog.2012.08.006. Epub 2012 Aug 10.
The objective of the study was to assess whether implementation of a statewide initiative was associated with changes in perinatal human immunodeficiency virus (HIV) testing practices.
This was an observational cohort study of all 1,141,799 women who delivered in Illinois birthing hospitals over a 7 year period after the introduction of the Perinatal Rapid Testing Implementation in Illinois (PRTII) initiative. Changes in the frequencies of HIV status documentation, rapid test utilization, and newborns discharged with unknown HIV status were assessed.
The comparison of annual data from 2005 to 2011 demonstrated a 63% decrease in women with undocumented HIV status (11.7% vs 4.3%, P < .001), a 98% decrease in women with unknown status who did not receive rapid testing (29.6% vs 0.5%, P < .001), and a greater than 99% decrease in newborns with undocumented status at discharge (2.74% vs 0.01%, P < .001).
This statewide initiative resulted in a significant and sustained increase in the frequency of maternal-baby pairs who were discharged from the hospital with documented HIV status.
本研究旨在评估在伊利诺伊州实施全州范围倡议是否与围产期人类免疫缺陷病毒（HIV）检测实践的变化相关。
这是一项观察性队列研究，纳入了在引入伊利诺伊州围产期快速检测实施倡议（PRTII）后 7 年内，在伊利诺伊州分娩医院分娩的所有 1141799 名女性。评估了 HIV 状态记录、快速检测利用以及新生儿出院时未知 HIV 状态的频率变化。
对 2005 年至 2011 年的年度数据进行比较，发现未记录 HIV 状态的女性比例下降了 63%（11.7%比 4.3%，P <.001），未接受快速检测且状态未知的女性比例下降了 98%（29.6%比 0.5%，P <.001），出院时未记录状态的新生儿比例下降了 99%以上（2.74%比 0.01%，P <.001）。
这项全州范围的倡议显著且持续地增加了母婴出院时记录 HIV 状态的比例。
