Department of Mechanical and Aerospace Engineering, University of California, San Diego, La Jolla, CA 92093, USA.
Acta Biomater. 2013 Feb;9(2):5280-8. doi: 10.1016/j.actbio.2012.08.040. Epub 2012 Aug 30.
The mechanical properties and microstructure of young and mature bovine femur bone were investigated by optical microscopy and compression testing in the longitudinal and transverse directions for untreated, deproteinized and demineralized cases. Optical microscopy revealed that mature bone has a more established and less porous microstructure compared to young bone. Mature bone was found to be stronger in both directions for the untreated and deproteinized cases. Mature untreated bone was also found to be stiffer and less tough compared to young bone in both directions. These results are related to the increase in mineralization of mature bone and significant microstructural differences. Young bone was found to be stronger in both directions for the demineralized case, which is attributed to alterations in the collagen network with age.
通过光学显微镜和纵向及横向压缩试验研究了幼牛和成年牛股骨的力学性能和微观结构，分别针对未处理、去蛋白和脱矿的情况。光学显微镜显示，成熟骨的微观结构比幼骨更完善且多孔性更小。对于未处理和去蛋白的情况，在两个方向上，成熟骨都比幼骨更强。在两个方向上，与幼骨相比，成熟未处理骨的刚性也更高，韧性也更低。这些结果与成熟骨矿化程度的增加和显著的微观结构差异有关。对于脱矿的情况，在两个方向上，幼骨的强度都更高，这归因于胶原网络随年龄的变化。
