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钯（II）-粪卟啉I作为寡核苷酸衍生物对核酸进行序列特异性修饰中的光可激活基团。

Palladium(II)-coproporphyrin I as a photoactivable group in sequence-specific modification of nucleic acids by oligonucleotide derivatives.

作者信息

Fedorova O S, Savitskii A P, Shoikhet K G, Ponomarev G V

机构信息

Institute of Bioorganic Chemistry, Siberian Division of the USSR Academy of Sciences, Novosibirsk.

出版信息

FEBS Lett. 1990 Jan 1;259(2):335-7. doi: 10.1016/0014-5793(90)80041-g.

DOI:10.1016/0014-5793(90)80041-g
PMID:2294023
Abstract

The 34-mer oligodeoxynucleotide was shown to be selectively modified at the G17 position upon photoirradiation in the presence of complementary 17-mer oligodeoxynucleotide bearing Pd(II)-coproporphyrin I covalently linked to the 5'-end phosphate group.

摘要

在存在与5'-末端磷酸基团共价连接的Pd(II)-粪卟啉I的互补17聚体寡脱氧核苷酸的情况下，经光照射后，34聚体寡脱氧核苷酸在G17位置被显示出被选择性修饰。

相似文献

1
Palladium(II)-coproporphyrin I as a photoactivable group in sequence-specific modification of nucleic acids by oligonucleotide derivatives.钯（II）-粪卟啉I作为寡核苷酸衍生物对核酸进行序列特异性修饰中的光可激活基团。
FEBS Lett. 1990 Jan 1;259(2):335-7. doi: 10.1016/0014-5793(90)80041-g.
2
Sequence-targeted photochemical modifications of nucleic acids by complementary oligonucleotides covalently linked to porphyrins.通过与卟啉共价连接的互补寡核苷酸对核酸进行序列靶向光化学修饰。
Bioconjug Chem. 1990 Mar-Apr;1(2):108-13. doi: 10.1021/bc00002a004.
3
Sequence-targeted photosensitized reactions in nucleic acids by oligo-alpha-deoxynucleotides and oligo-beta-deoxynucleotides covalently linked to proflavin.与原黄素共价连接的寡聚α-脱氧核苷酸和寡聚β-脱氧核苷酸在核酸中进行序列靶向的光敏反应。
Biochemistry. 1988 Apr 19;27(8):3031-8. doi: 10.1021/bi00408a055.
4
Difinite-sequenced oligonucleotides shackled with tetraphenylporphyrin: syntheses and properties.与四苯基卟啉相连的确定序列寡核苷酸：合成与性质
Nucleic Acids Symp Ser. 1995(34):185-6.
5
Evaluation of the phosphorescent palladium(II)-coproporphyrin labels in separation-free hybridization assays.
Anal Biochem. 2003 Sep 15;320(2):273-80. doi: 10.1016/s0003-2697(03)00383-x.
6
[Site-specific photomodification of nucleic acids with arylazide and perfluoroarylazide oligonucleotide derivatives. II. Specificity in relation to nucleosides].
Bioorg Khim. 1992 Sep;18(9):1190-8.
7
Synthesis and properties of oligonucleotide derivative with P(V) porphyrin.含磷（V）卟啉的寡核苷酸衍生物的合成与性质
Nucleic Acids Symp Ser. 1991(25):13-4.
8
[Complementary-addressed photomodification of nucleic acids by arylazide and perfluoroarylazide oligonucleotide derivatives. III. Oligonucleotide reagents with a photoactive group at the end or inside the chain; tandem reagents].[芳基叠氮化物和全氟芳基叠氮化物寡核苷酸衍生物对核酸的互补寻址光修饰。III. 链末端或链内带有光活性基团的寡核苷酸试剂；串联试剂]
Bioorg Khim. 1994 Jan;20(1):21-9.
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[Fluorescent immunoanalysis. Synthesis, spectro-fluorescent and immunologic properties of conjugates of coproporphyrin I with antibodies].[荧光免疫分析。粪卟啉原I与抗体结合物的合成、光谱荧光及免疫学特性]
Prikl Biokhim Mikrobiol. 1989 Jul-Aug;25(4):548-57.
10
[Effective complementarily-addressed photomodification of nucleic acids by oligonucleotide derivatives, containing aromatic azido groups].
Bioorg Khim. 1992 Apr;18(4):540-9.

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