Sakamaki Yasushi, Shiono Hiroyuki, Miura Takuya
Department of Chest Surgery, Osaka Police Hospital, Osaka, Japan.
Kyobu Geka. 2012 Sep;65(10):926-9.
An anterior mediastinal tumor was incidentally found in a 58-year-old asymptomatic woman on a medical checkup. Computed tomography (CT) demonstrated a large tumor plugging the almost entire lumen of the superior vena cava (SVC), and 3 nodules in the bilateral lungs. The tumor seemed most likely an advanced thymoma or thymic carcinoma extending into the SVC and presenting with lung metastases. The patient underwent a combined resection of the invasive tumor and the SVC under cardiopulmonary bypass (CPB), and lung wedge resection for the nodules. The bilateral brachiocephalic veins were reconstructed with the separate grafts. The invasive tumor and the lung nodules were histologically confirmed as thymoma. Resection and reconstruction of the SVC was successfully performed under CPB for extirpation of an invasive thymoma with extensive intracaval growth. Combination chemotherapy for the relapsing lung metastases finally achieved complete response 41 months after surgery.
一名58岁无症状女性在体检时偶然发现前纵隔肿瘤。计算机断层扫描(CT)显示一个大肿瘤几乎完全堵塞上腔静脉(SVC)管腔,并在双侧肺部有3个结节。该肿瘤最有可能是晚期胸腺瘤或胸腺癌,已延伸至SVC并伴有肺转移。患者在体外循环(CPB)下接受了侵袭性肿瘤与SVC的联合切除术,以及针对结节的肺楔形切除术。双侧头臂静脉用单独的移植物进行了重建。侵袭性肿瘤和肺结节经组织学确诊为胸腺瘤。在CPB下成功进行了SVC切除和重建,以切除具有广泛腔内生长的侵袭性胸腺瘤。针对复发性肺转移的联合化疗最终在术后41个月实现了完全缓解。