相似文献
1
Coupling endonucleases with DNA end-processing enzymes to drive gene disruption.
Nat Methods. 2012 Oct;9(10):973-5. doi: 10.1038/nmeth.2177. Epub 2012 Sep 2.
2
High frequency targeted mutagenesis using engineered endonucleases and DNA-end processing enzymes.
PLoS One. 2013;8(1):e53217. doi: 10.1371/journal.pone.0053217. Epub 2013 Jan 24.
3
The democratization of gene editing: Insights from site-specific cleavage and double-strand break repair.
DNA Repair (Amst). 2016 Aug;44:6-16. doi: 10.1016/j.dnarep.2016.05.001. Epub 2016 May 12.
4
Repair of endonuclease-induced double-strand breaks in Saccharomyces cerevisiae: essential role for genes associated with nonhomologous end-joining.
Genetics. 1999 Aug;152(4):1513-29. doi: 10.1093/genetics/152.4.1513.
5
Novel fluorescent genome editing reporters for monitoring DNA repair pathway utilization at endonuclease-induced breaks.
Nucleic Acids Res. 2014 Jan;42(1):e4. doi: 10.1093/nar/gkt872. Epub 2013 Oct 10.
6
Increasing the efficiency of precise genome editing with CRISPR-Cas9 by inhibition of nonhomologous end joining.
Nat Biotechnol. 2015 May;33(5):538-42. doi: 10.1038/nbt.3190. Epub 2015 Mar 23.
7
Harnessing accurate non-homologous end joining for efficient precise deletion in CRISPR/Cas9-mediated genome editing.
Genome Biol. 2018 Oct 19;19(1):170. doi: 10.1186/s13059-018-1518-x.
8
Targeted Modification of Gene Function Exploiting Homology-Directed Repair of TALEN-Mediated Double-Strand Breaks in Barley.
G3 (Bethesda). 2015 Jul 6;5(9):1857-63. doi: 10.1534/g3.115.018762.
9
Gene editing using ssODNs with engineered endonucleases.
Methods Mol Biol. 2015;1239:251-65. doi: 10.1007/978-1-4939-1862-1_14.
10
Modulating DNA Repair Pathways to Improve Precision Genome Engineering.
ACS Chem Biol. 2018 Feb 16;13(2):389-396. doi: 10.1021/acschembio.7b00777. Epub 2017 Dec 20.
引用本文的文献
1
Mitochondrial base editing: from principle, optimization to application.
Cell Biosci. 2025 Jan 24;15(1):9. doi: 10.1186/s13578-025-01351-8.
2
Engineering a robust Cas12i3 variant-mediated wheat genome editing system.
Plant Biotechnol J. 2025 Mar;23(3):860-873. doi: 10.1111/pbi.14544. Epub 2024 Dec 17.
3
Expanding plant genome editing scope and profiles with CRISPR-FrCas9 systems targeting palindromic TA sites.
Plant Biotechnol J. 2024 Sep;22(9):2488-2503. doi: 10.1111/pbi.14363. Epub 2024 May 7.
4
TREX2 enables efficient genome disruption mediated by paired CRISPR-Cas9 nickases that generate 3'-overhanging ends.
Mol Ther Nucleic Acids. 2023 Nov 2;34:102072. doi: 10.1016/j.omtn.2023.102072. eCollection 2023 Dec 12.
5
Strand-preferred base editing of organellar and nuclear genomes using CyDENT.
Nat Biotechnol. 2024 Jun;42(6):936-945. doi: 10.1038/s41587-023-01910-9. Epub 2023 Aug 28.
6
Targeted gene deletion with SpCas9 and multiple guide RNAs in Arabidopsis thaliana: four are better than two.
Plant Methods. 2023 Mar 28;19(1):30. doi: 10.1186/s13007-023-01010-4.
7
The high toxicity of DSB-clusters modelling high-LET-DNA damage derives from inhibition of c-NHEJ and promotion of alt-EJ and SSA despite increases in HR.
Front Cell Dev Biol. 2022 Oct 3;10:1016951. doi: 10.3389/fcell.2022.1016951. eCollection 2022.
8
To indel or not to indel: Factors influencing mutagenesis during chromosomal break end joining.
DNA Repair (Amst). 2022 Oct;118:103380. doi: 10.1016/j.dnarep.2022.103380. Epub 2022 Jul 30.
9
A Method for In Situ Reverse Genetic Analysis of Proteins Involved mtDNA Replication.
Cells. 2022 Jul 11;11(14):2168. doi: 10.3390/cells11142168.
10
Coiled-coil heterodimer-based recruitment of an exonuclease to CRISPR/Cas for enhanced gene editing.
Nat Commun. 2022 Jun 23;13(1):3604. doi: 10.1038/s41467-022-31386-1.
本文引用的文献
1
Revealing off-target cleavage specificities of zinc-finger nucleases by in vitro selection.
Nat Methods. 2011 Aug 7;8(9):765-70. doi: 10.1038/nmeth.1670.
2
Tracking genome engineering outcome at individual DNA breakpoints.
Nat Methods. 2011 Jul 10;8(8):671-6. doi: 10.1038/nmeth.1648.
3
Efficient design and assembly of custom TALEN and other TAL effector-based constructs for DNA targeting.
Nucleic Acids Res. 2011 Jul;39(12):e82. doi: 10.1093/nar/gkr218. Epub 2011 Apr 14.
4
Induction and repair of DNA double strand breaks: the increasing spectrum of non-homologous end joining pathways.
Mutat Res. 2011 Jun 3;711(1-2):61-72. doi: 10.1016/j.mrfmmm.2011.02.005. Epub 2011 Feb 15.
5
Chemokine receptor 5 knockout strategies.
Curr Opin HIV AIDS. 2011 Jan;6(1):74-9. doi: 10.1097/COH.0b013e32834122d7.
6
A TALE nuclease architecture for efficient genome editing.
Nat Biotechnol. 2011 Feb;29(2):143-8. doi: 10.1038/nbt.1755. Epub 2010 Dec 22.
7
Development of B-lineage predominant lentiviral vectors for use in genetic therapies for B cell disorders.
Mol Ther. 2011 Mar;19(3):515-25. doi: 10.1038/mt.2010.259. Epub 2010 Dec 7.
8
Genome editing with engineered zinc finger nucleases.
Nat Rev Genet. 2010 Sep;11(9):636-46. doi: 10.1038/nrg2842.
9
The mechanism of double-strand DNA break repair by the nonhomologous DNA end-joining pathway.
Annu Rev Biochem. 2010;79:181-211. doi: 10.1146/annurev.biochem.052308.093131.
10
Limiting the persistence of a chromosome break diminishes its mutagenic potential.
PLoS Genet. 2009 Oct;5(10):e1000683. doi: 10.1371/journal.pgen.1000683. Epub 2009 Oct 16.
Zotero 插件