Drinkwater B L, Bruemner B, Chesnut C H
Department of Medicine, Pacific Medical Center, Seattle, WA 98144.
JAMA. 1990 Jan 26;263(4):545-8.
The relationship of prior menstrual irregularities and current menstrual status to the bone density of 97 young athletes was determined at seven sites using single- and dual-photon absorptiometry. Menstrual patterns were ranked on a scale of 1 to 9 in terms of their potential adverse affect on bone. Only vertebral density was significantly related to menstrual patterns (r = -.43). Women who had always had regular cycles had higher lumbar densities (1.27 g/cm2) than those with a history of oligomenorrhea/amenorrhea interspersed with regular periods (1.18 g/cm2). The lumbar density of both groups exceeded that of women who had never had regular cycles (1.05 g/cm2). Body weight became more important as a predictor variable as the severity of menstrual irregularities increased. The combination of menstrual pattern and body weight predicted 43% of the total variation in lumbar density. These data suggest that extended periods of oligomenorrhea/amenorrhea may have a residual effect on lumbar bone density.
通过单光子和双光子吸收法，在97名年轻运动员的七个部位测定了既往月经不规律情况和当前月经状态与骨密度的关系。月经模式根据其对骨骼的潜在不良影响在1至9的范围内进行排名。只有椎体密度与月经模式显著相关（r = -0.43）。月经周期一直规律的女性腰椎密度（1.27克/平方厘米）高于有过月经稀发/闭经且夹杂规律经期病史的女性（1.18克/平方厘米）。两组的腰椎密度均超过从未有过规律月经周期的女性（1.05克/平方厘米）。随着月经不规律程度的增加，体重作为预测变量变得更为重要。月经模式和体重的组合可预测腰椎密度总变异的43%。这些数据表明，长期的月经稀发/闭经可能对腰椎骨密度有残留影响。
