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他达拉非和乙酰唑胺与乙酰唑胺预防严重高原病的比较。

Tadalafil and acetazolamide versus acetazolamide for the prevention of severe high-altitude illness.

机构信息

Center for Geographic Medicine and Internal Medicine C, Sheba Medical Center, Tel-Hashomer and Sackler Faculty of Medicine, Tel Aviv, Israel.

出版信息

J Travel Med. 2012 Sep-Oct;19(5):308-10. doi: 10.1111/j.1708-8305.2012.00636.x. Epub 2012 Jul 30.

DOI:10.1111/j.1708-8305.2012.00636.x
PMID:22943271
Abstract

We report an open-label study comparing tadalafil and acetazolamide (n = 24) versus acetazolamide (n = 27) for prevention of high-altitude illness (HAI) at Mt. Kilimanjaro. Tadalafil group had lower rates of severe HAI compared with controls (4% vs 26%, p = 0.03), mostly because of decreased high-altitude pulmonary edema rates (4% vs 22%, p = 0.06).

摘要

我们报告了一项开放性研究，比较了他达拉非和乙酰唑胺（n=24）与乙酰唑胺（n=27）在预防乞力马扎罗山高原病（HAI）方面的效果。与对照组相比，他达拉非组严重 HAI 的发生率较低（4%比 26%，p=0.03），主要是因为高原肺水肿的发生率降低（4%比 22%，p=0.06）。

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Tadalafil and acetazolamide versus acetazolamide for the prevention of severe high-altitude illness.他达拉非和乙酰唑胺与乙酰唑胺预防严重高原病的比较。
J Travel Med. 2012 Sep-Oct;19(5):308-10. doi: 10.1111/j.1708-8305.2012.00636.x. Epub 2012 Jul 30.
2
Acclimatizing with acetazolamide.用乙酰唑胺进行适应性训练。
J Travel Med. 2012 Sep-Oct;19(5):281-3. doi: 10.1111/j.1708-8305.2012.00646.x.
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Prophylactic low-dose acetazolamide reduces the incidence and severity of acute mountain sickness.预防性低剂量乙酰唑胺可降低急性高原病的发病率和严重程度。
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Acetazolamide or not, prior to ascent?在登高前是否服用乙酰唑胺？
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Age is no barrier to success at very high altitudes.在极高海拔地区，年龄并非成功的障碍。
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[Your patient wants to go to the mountains. You protect him from mountain sickness and altitude edema].[你的患者想去山区。你要保护他预防高山病和高原水肿。]
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Low-dose acetylsalicylic Acid analog and acetazolamide for prevention of acute mountain sickness.低剂量乙酰水杨酸类似物和乙酰唑胺预防急性高原病
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