Department of Computed Tomography, The 452nd Hospital of PLA, Chengdu 610061, Sichuan Province, China.
World J Surg Oncol. 2012 Sep 3;10:182. doi: 10.1186/1477-7819-10-182.
Pulmonary sclerosing hemangioma (PSH) is a rare benign tumor of the lungs. These tumors are composed of cuboidal surface cells and polygonal stromal cells and show four histological manifestations: hemorrhagic, papillary, solid, and sclerotic. PSH predominantly affects asymptomatic middle-aged women. The tumor often occurs at the intralobar site, and less commonly in the bronchus and mediastinum. PSH is easy to be misdiagnosed preoperatively. In this study, we present in detail the treatment procedures followed for two atypical cases of PSH. Case 1 was a 62-year-old woman bearing a tumor for 15 years. The tumor lesion was found to be located in the oblique fissure of the left lung. PSH was confirmed by surgical resection and postoperative pathological diagnosis. There was no sign of recurrence and metastasis 1.5 years after surgery. Case 2 was a 54-year-old woman diagnosed with bilateral multiple nodules by physical examination. This patient was diagnosed with definite PSH through computed tomography-guided percutaneous lung biopsy. Surgical resection was not performed. The patient also showed no sign of enlarged tumor and metastasis after 2 years of follow-up. Although PSH can be cured by surgical resection, the findings in our cases indicate that surgical resection need not be considered the preferred course of treatment. If PSH is diagnosed before surgery, the patients may survive while bearing the tumor.
肺硬化性血管瘤(PSH)是一种罕见的肺部良性肿瘤。这些肿瘤由立方状的表面细胞和多边形的基质细胞组成,表现出四种组织学表现:出血性、乳头状、实性和硬化性。PSH 主要影响无症状的中年女性。肿瘤常发生于肺叶内部位,较少发生于支气管和纵隔。PSH 术前易误诊。本研究详细介绍了两例非典型 PSH 病例的治疗过程。病例 1 为 62 岁女性,肿瘤病史 15 年。肿瘤病变位于左肺斜裂。经手术切除和术后病理诊断为 PSH。术后 1.5 年无复发转移迹象。病例 2 为 54 岁女性,体检发现双侧多发结节。该患者经 CT 引导下经皮肺活检诊断为明确的 PSH,未行手术切除。2 年随访后,患者肿瘤未见增大和转移。虽然手术切除可以治愈 PSH,但我们的病例结果表明,手术切除不一定是首选的治疗方法。如果在术前诊断出 PSH,患者可能会在携带肿瘤的情况下存活。