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Non-fibrillar collagens: key mediators of post-infarction cardiac remodeling?非纤维胶原：心肌梗死后心脏重构的关键介质？
J Mol Cell Cardiol. 2010 Mar;48(3):530-7. doi: 10.1016/j.yjmcc.2009.06.017. Epub 2009 Jun 30.
2
MicroRNA-21 contributes to myocardial disease by stimulating MAP kinase signalling in fibroblasts.微小RNA-21通过刺激成纤维细胞中的丝裂原活化蛋白激酶信号传导，导致心肌疾病。
Nature. 2008 Dec 18;456(7224):980-4. doi: 10.1038/nature07511. Epub 2008 Nov 30.
3
Myofibroblast contraction activates latent TGF-beta1 from the extracellular matrix.肌成纤维细胞收缩可激活细胞外基质中的潜伏性转化生长因子β1。
J Cell Biol. 2007 Dec 17;179(6):1311-23. doi: 10.1083/jcb.200704042.
4
Essential role of Smad3 in infarct healing and in the pathogenesis of cardiac remodeling.Smad3在梗死愈合及心脏重塑发病机制中的重要作用。
Circulation. 2007 Nov 6;116(19):2127-38. doi: 10.1161/CIRCULATIONAHA.107.704197. Epub 2007 Oct 22.
5
In vitro scratch assay: a convenient and inexpensive method for analysis of cell migration in vitro.体外划痕试验：一种用于体外细胞迁移分析的简便且经济的方法。
Nat Protoc. 2007;2(2):329-33. doi: 10.1038/nprot.2007.30.
6
Smad3 deficiency alters key structural elements of the extracellular matrix and mechanotransduction of wound closure.Smad3基因缺陷会改变细胞外基质的关键结构成分以及伤口愈合的机械转导过程。
Proc Natl Acad Sci U S A. 2006 Jun 13;103(24):9250-5. doi: 10.1073/pnas.0602473103. Epub 2006 Jun 5.
7
An exploration of two opposing theories of wound contraction.
J Wound Care. 2004 Apr;13(4):138-40. doi: 10.12968/jowc.2004.13.4.26604.
8
Mechanical force regulation of myofibroblast differentiation in cardiac fibroblasts.心肌成纤维细胞中肌成纤维细胞分化的机械力调节
Am J Physiol Heart Circ Physiol. 2003 Nov;285(5):H1871-81. doi: 10.1152/ajpheart.00387.2003. Epub 2003 Jul 3.
9
Transforming growth factor-beta 1-mediated collagen gel contraction by cardiac fibroblasts.转化生长因子-β1介导的心肌成纤维细胞胶原凝胶收缩
J Renin Angiotensin Aldosterone Syst. 2003 Jun;4(2):113-8. doi: 10.3317/jraas.2003.011.
10
Diversity, topographic differentiation, and positional memory in human fibroblasts.人类成纤维细胞中的多样性、地形分化和位置记忆。
Proc Natl Acad Sci U S A. 2002 Oct 1;99(20):12877-82. doi: 10.1073/pnas.162488599. Epub 2002 Sep 24.

心脏成肌纤维细胞：失衡的细胞。一个新的主题系列。

Cardiac myofibroblasts: cells out of balance. A new thematic series.

作者信息

Dixon Ian M C

机构信息

Principal Investigator, Laboratory of Molecular Cardiology, Department of Physiology, Faculty of Medicine and the Institute of Cardiovascular Sciences, St, Boniface General Hospital Research Centre, University of Manitoba, 351 Tache Ave, Manitoba, R2H 2A6, Winnipeg, Canada.

出版信息

Fibrogenesis Tissue Repair. 2012 Sep 3;5(1):14. doi: 10.1186/1755-1536-5-14.

DOI:10.1186/1755-1536-5-14
PMID:22943486
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC3563470/
Abstract

We are pleased to introduce a new thematic series dealing with cardiac fibrosis and its association with cardiovascular diseases. A wide variety of cardiovascular diseases are associated with cardiac fibrosis, which is now widely recognized to be not a secondary, but rather a primary contributor to cardiac dysfunction. The purpose of the current series of papers and reviews is to provide the reader with an up-to-date synopsis of the very latest research results and hypotheses that impact on cardiac fibrosis and disease.

摘要

我们很高兴推出一个关于心脏纤维化及其与心血管疾病关联的新主题系列。多种心血管疾病都与心脏纤维化有关，目前人们普遍认识到，心脏纤维化并非心脏功能障碍的次要因素，而是主要因素。本系列论文和综述的目的是为读者提供有关影响心脏纤维化和疾病的最新研究成果及假说的最新概要。