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双相障碍症状和功能恢复的心理教育疗效。

Efficacy of psychoeducation on symptomatic and functional recovery in bipolar disorder.

机构信息

Mood Disorders Unit (GRUDA), Department and Institute of Psychiatry, Clinicas Hospital, University of Sao Paulo, School of Medicine, Sao Paulo, Brazil.

出版信息

Acta Psychiatr Scand. 2013 Feb;127(2):153-8. doi: 10.1111/acps.12007. Epub 2012 Sep 4.

DOI:10.1111/acps.12007
PMID:22943487
Abstract

OBJECTIVE

To evaluate the efficacy of psychoeducation in the symptomatic and functional recovery, and quality of life (QoL) in a sample of patients with bipolar disorder (BD).

METHOD

The sample comprised 55 patients with BD I and II in remission (Young Mania Rating Scale ≤6 and Hamilton Depression Rating Scale ≤7). Out-patients were matched assigned to receive 16 sessions of psychoeducation [experimental group (EG)] or 16 sessions of placebo without psychoeducation [control group (CG)]. Groups were evaluated at study baseline, midpoint, endpoint, and at 6- and 12-month follow-ups.

RESULTS

No significant differences between the groups were found for the variables evaluated (mood symptoms, functioning and QoL), except for overall clinical improvement, subjectively perceived by EG subjects. Both groups showed a trend toward improved clinical global impression and QoL (environmental). No reduction in mood symptoms or improvement in psychosocial functioning was observed. Psychosocial treatment compliance was positively correlated with global functioning, social adjustment, sociability, and global clinical impression.

CONCLUSION

Sixteen session psychoeducation seems to be ineffective to prevent mood episodes or improve functioning in a sample of bipolar patients.

摘要

目的

评估心理教育对缓解期双相情感障碍(BD)患者症状和功能恢复以及生活质量(QoL)的疗效。

方法

该样本包括 55 名缓解期(Young 躁狂评定量表≤6 分和 Hamilton 抑郁评定量表≤7 分)的 I 型和 II 型 BD 患者。门诊患者按匹配分组接受 16 节心理教育[实验组(EG)]或 16 节无心理教育的安慰剂[对照组(CG)]。在研究基线、中点、终点以及 6 个月和 12 个月随访时对两组进行评估。

结果

除 EG 组主观感知的整体临床改善外,两组在评估的变量(情绪症状、功能和 QoL)方面均无显著差异。两组均表现出临床总体印象和 QoL(环境)改善的趋势。情绪症状没有减轻,心理社会功能也没有改善。心理社会治疗的依从性与总体功能、社会适应、社交能力和总体临床印象呈正相关。

结论

在双相情感障碍患者样本中,16 节心理教育似乎不能预防情绪发作或改善功能。

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