High-throughput whole genome analysis provides insight into how the major drugs against African sleeping sickness operate.
作者信息
Rudenko Gloria
机构信息
Imperial College, London, UK.
出版信息
Pathog Glob Health. 2012 May;106(2):79. doi: 10.1179/204777312X13419245939601.
Abstract
摘要
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本文引用的文献
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High-throughput decoding of antitrypanosomal drug efficacy and resistance.高通量解码抗锥虫药物疗效和耐药性。
Nature. 2012 Jan 25;482(7384):232-6. doi: 10.1038/nature10771.
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High-throughput phenotyping using parallel sequencing of RNA interference targets in the African trypanosome.使用 RNA 干扰靶点的平行测序进行高通量表型分析。
Genome Res. 2011 Jun;21(6):915-24. doi: 10.1101/gr.115089.110. Epub 2011 Mar 1.
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The Atlas of human African trypanosomiasis: a contribution to global mapping of neglected tropical diseases.人类非洲锥虫病图集：对被忽视热带病全球绘图的贡献。
Int J Health Geogr. 2010 Nov 1;9:57. doi: 10.1186/1476-072X-9-57.
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Trypanocidal drugs: mechanisms, resistance and new targets.抗锥虫药物：作用机制、耐药性及新靶点
Expert Rev Mol Med. 2009 Oct 29;11:e31. doi: 10.1017/S1462399409001252.
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