Department of Pediatrics, Philipps University, Marburg, Germany.
J Pediatr. 2012 Dec;161(6):1172-4. doi: 10.1016/j.jpeds.2012.07.051. Epub 2012 Aug 31.
Here we show that the frequency of T(H)17 cells (CD3(+)CD4(+)CD161(+)CCR6(+) lymphocytes) is increased in peripheral blood of children with allergic asthma. Moreover, we found a significant relationship between the frequency of T(H)17 cells and level of asthma control, with reduced asthma control correlated with a higher proportion of T(H)17 cells.
在这里，我们表明过敏性哮喘患儿外周血中 T(H)17 细胞（CD3(+)CD4(+)CD161(+)CCR6(+) 淋巴细胞）的频率增加。此外，我们还发现 T(H)17 细胞的频率与哮喘控制水平之间存在显著关系，哮喘控制降低与 T(H)17 细胞比例升高相关。
