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[牙髓干细胞:特性、冷冻保存及治疗潜力]

[Dental pulp stem cells: characteristics, cryopreservation and therapeutic potentialities].

作者信息

Collart Dutilleul Pierre-Yves, Thonat Catherine, Jacquemart Pierre, Cuisinier Frédéric, Levallois Bernard, Chaubron Franck

机构信息

Laboratoire BioSanté et Nanoscience EA 4203, UFR Odontologie, 545 avenue Pr. Jean-Louis Viala, 34193 Montpellier Cedex 5, France.

出版信息

Orthod Fr. 2012 Sep;83(3):209-16. doi: 10.1051/orthodfr/2012020. Epub 2012 Sep 5.

DOI:10.1051/orthodfr/2012020
PMID:22944014
Abstract

Stem cells discovery and their potential have led to the emergence of new forms of therapy with the development of bio-engineering cell and tissue methods underlying future medicine. The availability of stem cells and their preservation thus become an issue for everyone's health. Among the different sources of stem cells, those in the dental pulp have the advantage of being pluripotent, they can be cryopreserved and stored for long periods without losing their multiplication and differentiation capacities and finally they are easily accessible. The wisdom or natal teeth extracted for medical reasons are an opportunity for everyone to preserve stem cells for an autologous use. Biobanks authorized and specialized in the preparation and storage of pulp stem cells provide access to autologous regenerative medicine of tomorrow.

摘要

干细胞的发现及其潜力促使了新治疗形式的出现,这得益于生物工程细胞和组织方法的发展,这些方法构成了未来医学的基础。因此,干细胞的可得性及其保存成为关乎每个人健康的问题。在不同的干细胞来源中,牙髓干细胞具有多能性的优势,它们可以被冷冻保存很长时间而不丧失增殖和分化能力,并且最终易于获取。因医疗原因拔除的智齿或乳牙为每个人提供了保存干细胞以供自体使用的机会。经授权且专门从事牙髓干细胞制备和储存的生物样本库为未来的自体再生医学提供了途径。

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