Zhang Jia-shu, Chen Xiao-lei, Li Fang-ye, Li Jin-jiang, Zheng Gang, Zhang Ting, Hu Shen, Xu Bai-nan
Department of Neurosurgery, PLA General Hospital, Beijing 100853, China.
Zhonghua Yi Xue Za Zhi. 2012 Jun 5;92(21):1468-71.
To evaluate the clinical value of VarioGuide in stereotactic brain biopsy.
Fifteen patients with brain lesions underwent frameless stereotactic brain biopsy guided by VarioGuide and multimodal neuronavigation. Intraoperative magnetic resonance imaging (iMRI) was used to confirm the accuracy of biopsy. And the VarioGuide-related adverse events, operative duration, surgical outcomes and postoperative complications were recorded respectively.
In all patients, VarioGuide and multimodal neuronavigation were successfully integrated into the biopsy procedure. No VarioGuide-related adverse events were reported. The mean operative duration was (65 ± 8) min. The biopsy accuracy was confirmed by iMRI in all cases. And the postoperative histological diagnostic rate was 100%. No mortality and morbidity occurred postoperatively.
The combined approach of VarioGuide and multimodal neuronavigation is accurate, safe and efficient. It may improve the histological diagnostic rate without postoperative neurological deficits in stereotactic brain biopsy.
评估VarioGuide在立体定向脑活检中的临床价值。
15例脑病变患者在VarioGuide和多模态神经导航引导下进行了无框架立体定向脑活检。术中磁共振成像（iMRI）用于确认活检的准确性。分别记录与VarioGuide相关的不良事件、手术时长、手术结果及术后并发症。
所有患者中，VarioGuide和多模态神经导航均成功整合入活检过程。未报告与VarioGuide相关的不良事件。平均手术时长为（65±8）分钟。所有病例的活检准确性均经iMRI确认。术后组织学诊断率为100%。术后未发生死亡及并发症。
VarioGuide与多模态神经导航相结合的方法准确、安全且高效。在立体定向脑活检中，它可能提高组织学诊断率且不导致术后神经功能缺损。
