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影响极低出生体重早产儿肠系膜上动脉血流速度产后增加的因素。

Factors that affect the postnatal increase in superior mesenteric artery blood flow velocity in very low birth weight preterm infants.

机构信息

Saint Louis University-Pediatrics, 1465 South Grand Blvd, St. Louis, MO 63104, USA.

出版信息

J Perinat Med. 2012 Apr 15;40(5):565-70. doi: 10.1515/jpm-2011-0235.

DOI:10.1515/jpm-2011-0235
PMID:22945276
Abstract

OBJECTIVE

To identify factors related to the postnatal increase in superior mesenteric artery blood flow velocity (SMA BFV).

STUDY DESIGN

SMA BFV was measured in 35 infants (birth weight 1047±246 g) on day of life (DOL) 1, 3, 5, 7 10 and 14. Latent curve modeling (LCM) was used to measure the longitudinal change in BFV for each subject, and the correlation between changes in BFV and baseline values. Non-parametric correlations were calculated between BFV and variables previously reported to be related to SMA BFV.

RESULTS

There was significant variability in SMA BFV on DOL 1, a significant increase from DOL 1-14, and significant variability in the postnatal increase. Infants with higher enteral feeding volumes had greater increases, while infants receiving positive pressure ventilation or hyperalimentation had lower increases.

CONCLUSIONS

Several clinical factors affect the postnatal increase in SMA BFV. The use of LCM is useful in longitudinal studies of very low birth weight (VLBW) infants, who are clinically and demographically heterogeneous.

摘要

目的

确定与肠系膜上动脉血流速度(SMA BFV)产后增加相关的因素。

研究设计

在出生后第 1、3、5、7、10 和 14 天,对 35 名婴儿(出生体重 1047±246g)测量 SMA BFV。使用潜在曲线建模(LCM)测量每位受试者 BFV 的纵向变化,并测量 BFV 的变化与基线值之间的相关性。计算 BFV 与先前报道与 SMA BFV 相关的变量之间的非参数相关性。

结果

在出生后第 1 天,SMA BFV 存在显著的变异性,从出生后第 1 天到第 14 天有显著的增加,并且产后增加存在显著的变异性。接受较高肠内喂养量的婴儿增加幅度较大,而接受正压通气或高营养支持的婴儿增加幅度较小。

结论

几个临床因素影响 SMA BFV 的产后增加。LCM 的使用对于极低出生体重(VLBW)婴儿的纵向研究非常有用,这些婴儿在临床和人口统计学上存在异质性。

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J Perinat Med. 2012 Apr 15;40(5):565-70. doi: 10.1515/jpm-2011-0235.
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