Van Bel F, Van Zwieten P H, Guit G L, Schipper J
Department of Pediatrics, University Hospital of Leiden, The Netherlands.
Radiology. 1990 Jan;174(1):165-9. doi: 10.1148/radiology.174.1.2403678.
To obtain information about intestinal hemodynamics of healthy neonates, the authors assessed velocity and volume of blood flow with duplex Doppler sonography in the superior mesenteric artery (SMA) in 91 stable preterm and term neonates. Blood flow velocity in the SMA and estimated volume blood flow increased linearly with gestational age and increasing body weight. The mean estimated volume blood flow (+/- standard deviation) was 43 mL/kg/min +/- 13 and did not depend on differences in body weight. The authors also assessed blood flow velocity in the SMA and volume blood flow in 18 infants with conditions that may affect blood supply to the bowel. Twelve infants who were small for gestational age appeared to have an abnormally low resistance of the vascular bed of the SMA during the 1st days of life, as compared with stable appropriate-for-gestational-age infants matched for gestational age. Three of six term neonates with cardiovascular abnormalities had left ventricular outflow obstruction and an abnormal blood flow velocity waveform of the SMA, suggesting a decrease in blood supply to the bowel. The results of this study may help in evaluations of intestinal perfusion in infants with abnormal conditions.
为获取健康新生儿肠道血流动力学的信息，作者采用双功多普勒超声检查法评估了91例病情稳定的早产和足月新生儿肠系膜上动脉（SMA）的血流速度和血流量。SMA的血流速度和估计的血流量随胎龄和体重增加呈线性增加。估计的平均血流量（±标准差）为43 mL/kg/min±13，且不依赖于体重差异。作者还评估了18例可能影响肠道血液供应疾病患儿的SMA血流速度和血流量。与胎龄匹配的病情稳定的适于胎龄儿相比，12例小于胎龄儿在出生后第1天SMA血管床阻力似乎异常低。6例患有心血管异常的足月新生儿中有3例存在左心室流出道梗阻及SMA血流速度波形异常，提示肠道血液供应减少。本研究结果可能有助于评估病情异常患儿的肠道灌注情况。
