Department of Neurosurgery, Charité-Universitätsmedizin Berlin, Augustenburger Platz 1, 13353 Berlin, Germany.
Acta Neurochir (Wien). 2012 Nov;154(11):2003-8; discussion 2008. doi: 10.1007/s00701-012-1492-0. Epub 2012 Sep 4.
We report on a patient with LGG, in whom NBS mapping confirmed relocation of the primary motor cortex (M1) concurrent with multistage surgery. Comparing the NBS results at 18 months with the initial results revealed that the M1 representation had shifted from the precentral to the postcentral gyrus. The patient underwent a third surgical intervention. Intraoperative direct cortical stimulation (DCS) confirmed the shift of the M1. Plastic changes in M1 localization permitted complete tumour removal without neurological sequela. To our knowledge, this is the first report on a LGG patient where induced brain plasticity has been confirmed by NBS mapping.
我们报告了一例 LGG 患者，在该患者中，NBS 图谱证实原发性运动皮层（M1）的位置同时发生了多阶段手术改变。将 18 个月时的 NBS 结果与初始结果进行比较，结果显示 M1 代表区已从前中央回转移到后中央回。患者接受了第三次手术干预。术中直接皮层刺激（DCS）证实了 M1 的移位。M1 定位的可塑性变化使得肿瘤能够完全切除而无神经后遗症。据我们所知，这是首例通过 NBS 图谱证实 LGG 患者诱导脑可塑性的报告。
