Joubert J, Jenni W K
Department of Neurology, Medical University of Southern Africa, Pretoria.
S Afr Med J. 1990 Jan 6;77(1):27-30.
The clinical and laboratory data of 88 black patients with computed tomographic (CT) evidence of active neurocysticercosis were analysed. The CT appearance of neurocysticercosis was distinctive in the majority. Seizures, chronic headache and neuropsychiatric changes were the most common clinical presentations. Hydrocephalus was diagnosed in 17 patients (9 obstructive and 8 communicating) and cerebral infarction with focal neurological deficit occurred in 4 cases. All patients were treated with praziquantel (Biltricide: Bayer Miles). There was complete cyst clearance after two courses in 14 patients and in 16 cases the mean percentage reduction in cyst number was 85.88% and in cyst size 80.84%. In 1 patient there was no response to treatment. Although praziquantel was effective in parenchymal neurocysticercosis, it was ineffectual in the treatment of 5 patients with cysticercal meningitis. There were 2 deaths in the series.
对88例有计算机断层扫描（CT）证据显示患有活动性神经囊尾蚴病的黑人患者的临床和实验室数据进行了分析。大多数患者神经囊尾蚴病的CT表现具有特征性。癫痫发作、慢性头痛和神经精神改变是最常见的临床表现。17例患者被诊断为脑积水（9例梗阻性和8例交通性），4例发生伴有局灶性神经功能缺损的脑梗死。所有患者均接受吡喹酮（拜耳公司的必奇）治疗。14例患者在两个疗程后囊肿完全清除，16例患者囊肿数量平均减少85.88%，囊肿大小平均减少80.84%。1例患者对治疗无反应。虽然吡喹酮对实质性神经囊尾蚴病有效，但对5例囊尾蚴性脑膜炎患者的治疗无效。该系列中有2例死亡。
