Joubert J
Department of Neurology, Medical University of Southern Africa, Pretoria.
S Afr Med J. 1990 May 19;77(10):528-30.
Chronic cysticercal meningitis was diagnosed in 6 of 260 cases of neurocysticercosis. Clinical features usually associated with meningitis, such as fever, cranial nerve palsies and nuchal rigidity, were absent and the diagnosis was reached because of persistently abnormal cerebrospinal fluid (CSF) associated with active neurocysticercosis on computed tomography. Other causes of chronic meningitis were excluded. Hydrocephalus, either obstructive or communicating, was present in all 6 patients. The results of medical treatment with praziquantel were poor and there was no improvement either clinically or in the CSF. Severe clinical sequelae, such as dementia, blindness and gait ataxia, were common despite protracted medical treatment and ventriculoperitoneal shunting.
在260例神经囊尾蚴病患者中,有6例被诊断为慢性囊尾蚴性脑膜炎。通常与脑膜炎相关的临床特征,如发热、颅神经麻痹和颈项强直并不存在,诊断是因为计算机断层扫描显示脑脊液(CSF)持续异常且伴有活动性神经囊尾蚴病。其他慢性脑膜炎的病因已被排除。所有6例患者均存在梗阻性或交通性脑积水。吡喹酮药物治疗效果不佳,临床症状和脑脊液均无改善。尽管进行了长期的药物治疗和脑室腹腔分流术,但严重的临床后遗症,如痴呆、失明和步态共济失调仍很常见。