Department of Agroenvironmental Sciences and Technologies, Microbiology Area, Alma Mater Studiorum-University of Bologna, Bologna, Italy.
Int J Food Sci Nutr. 2013 Mar;64(2):162-8. doi: 10.3109/09637486.2012.718742. Epub 2012 Sep 5.
Synbiotic dietary supplements are used to modulate the intestinal microbiota in adults; however, studies regarding elderly people are limited. The aim of this work is to determine the effect of regular consumption of yogurt containing Lactobacillus rhamnosus GG (LGG) and the fructooligosaccharide (FOS) Actilight(®) both in healthy adults and the elderly suffering from constipation. Yogurt was administered daily for 4 weeks; faecal samples were collected before starting, after 4-week administration and a 15-day wash out period, and analyzed for LGG and bifidobacteria counts. Constipation status in the elderly was recorded by a standardized questionnaire. Bifidobacteria did not increase in either groups; at the end of the intervention trial, LGG was detected in significantly different amount in the faeces of the elderly and adults, being higher in adults (95% vs. 30%). An increased evacuation number in the elderly was evidenced, probably due to the presence of FOS in yogurt.
合生元膳食补充剂被用于调节成年人的肠道微生物群;然而,关于老年人的研究有限。本研究的目的是确定常规食用含有鼠李糖乳杆菌 GG(LGG)和低聚果糖(FOS)Actilight®的酸奶对健康成年人和便秘老年人的影响。酸奶每天服用 4 周;在开始前、4 周给药后和 15 天的洗脱期收集粪便样本,并分析 LGG 和双歧杆菌的计数。老年人的便秘状况通过标准化问卷记录。双歧杆菌在两组中均未增加;在干预试验结束时,老年人粪便中的 LGG 含量明显不同,成年人的含量更高(95%比 30%)。在老年人中观察到排便次数增加,这可能是由于酸奶中存在 FOS。