Detroit Medical Center, Wayne State University, Detroit, MI, USA.
Heart Fail Rev. 2013 Jul;18(4):485-501. doi: 10.1007/s10741-012-9342-y.
Anemia and iron deficiency are quite prevalent in patients with heart failure (HF) and may overlap. Both anemia and iron deficiency are associated with worse symptoms and adverse clinical outcomes. In the past few years, there has been an enormous interest in the subject of iron deficiency and its management in patients with HF. In this review, the etiology and relevance of iron deficiency, iron metabolism in the setting of HF, studies on iron supplementation in patients with HF and potential cardiovascular effects of subclinical iron overload are discussed.
贫血和缺铁在心力衰竭（HF）患者中很常见，并且可能重叠。贫血和缺铁均与更严重的症状和不良临床结局相关。在过去几年中，人们对 HF 患者中铁缺乏及其管理这一主题产生了浓厚的兴趣。在这篇综述中，讨论了铁缺乏的病因和相关性、HF 患者铁代谢、HF 患者铁补充研究以及亚临床铁过载的潜在心血管影响。
